HitPredict

Interactor 1: SHC1 (P98083)
SHC-transforming protein 1 (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: GAB1 (Q9QYY0)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.636

The method score is based on:

Property Details
Experiments 12808090, 11707404, 10871282
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0007507 - heart development
GO:0043410 - positive regulation of MAPK cascade
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 579
Mm

1 695
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 11Aug2025