Interactor 1: ESR1 (P19785)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1
Interactor 2: LEF1 (P27782)
Lymphoid enhancer-binding factor 1 (LEF-1)
Gene: LEF1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18202148 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001222 - transcription corepressor binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003682 - chromatin binding GO:0005634 - nucleus and 10 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
