Protein: PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2)

Gene: PLCB2
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q00722

Gene Ontology (top 5):
GO:0001580 - detection of chemical stimulus involved in sensory perception of bitter taste
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0004629 - phospholipase C activity
GO:0005509 - calcium ion binding
GO:0005543 - phospholipid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

988285

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

Small-scale

0.647

High

893481

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

3

Small-scale

0.618

High

1026941

WDR26
WD repeat-containing protein 26

1

2

Small-scale

0.618

High

858632

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

3

Small-scale

0.573

High

1026942

CTNL1
Alpha-catulin

1

2

Small-scale

0.536

High

1026935

PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

1

5

Small-scale

0.527

High

1026940

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

4

Small-scale

0.523

High

912497

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

3

Small-scale

0.515

High

791297

SYUA
Alpha-synuclein

1

2

Small-scale

0.501

High

1026938

MK14
Mitogen-activated protein kinase 14

1

0

Small-scale

0.493

High

461367

HS90A
Heat shock protein HSP 90-alpha

1

2

High-throughput

0.479

High

640507

TA2R
Thromboxane A2 receptor

1

3

Small-scale

0.479

High

1026936

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

991970

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.458

High

1026937

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

5

Small-scale

0.437

High

1026943

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.437

High

536982

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.426

High

74465

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.269

Low

1026939

WDR36
WD repeat-containing protein 36

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025