Protein: WDR26
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)

Gene: WDR26
Organism: Homo sapiens
Interactions: 180
UniProt ID: Q9H7D7

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

971089

UBE2H
Ubiquitin-conjugating enzyme E2 H

3

14

High-throughput

0.847

High

181177

AXIN1
Axin-1

2

5

Small-scale

0.773

High

1402306

RANB9
Ran-binding protein 9

8

19

Small-scale

0.747

High

1157932

DDB1
DNA damage-binding protein 1

2

14

Small-scale

0.737

High

1227469

A16L1
Autophagy-related protein 16-1

2

18

High-throughput

0.737

High

1435660

RMD5A
E3 ubiquitin-protein transferase RMND5A

6

10

Small-scale

0.733

High

1307929

ARMC8
Armadillo repeat-containing protein 8

5

15

Small-scale

0.712

High

1435665

GID8
Glucose-induced degradation protein 8 homolog

5

13

Small-scale

0.712

High

1250525

RBP10
Ran-binding protein 10

4

18

High-throughput

0.694

High

1409944

DDX50
ATP-dependent RNA helicase DDX50

1

14

High-throughput

0.691

High

1435670

MRM2
rRNA methyltransferase 2, mitochondrial

1

3

High-throughput

0.691

High

1272748

MAEA
E3 ubiquitin-protein transferase MAEA

3

13

Small-scale

0.674

High

983577

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

3

16

Small-scale

0.669

High

848176

MAGA1
Melanoma-associated antigen 1

3

14

High-throughput

0.667

High

948079

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

11

Small-scale

0.662

High

872025

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

6

High-throughput

0.662

High

1104675

IKZF1
DNA-binding protein Ikaros

3

9

High-throughput

0.662

High

1309312

GID4
Glucose-induced degradation protein 4 homolog

3

1

Small-scale

0.656

High

1435673

MKLN1
Muskelin

3

11

Small-scale

0.656

High

1418242

RM04
Large ribosomal subunit protein uL4m

3

0

High-throughput

0.638

High

1051318

KPCZ
Protein kinase C zeta type

3

11

High-throughput

0.633

High

230665

PRIC3
Prickle planar cell polarity protein 3

2

11

High-throughput

0.628

High

1198319

TIGD5
Tigger transposable element-derived protein 5

2

2

High-throughput

0.628

High

555427

SKI
Ski oncogene

3

0

Small-scale

0.628

High

1369133

COR2A
Coronin-2A

1

20

High-throughput

0.618

High

159859

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

12

Small-scale

0.618

High

275920

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

10

Small-scale

0.618

High

316018

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.618

High

724425

COR1A
Coronin-1A

1

19

Small-scale

0.618

High

728623

AKT2
RAC-beta serine/threonine-protein kinase

1

9

Small-scale

0.618

High

839176

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

10

Small-scale

0.618

High

967176

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

10

Small-scale

0.618

High

1007784

RAE1L
mRNA export factor RAE1

1

20

High-throughput

0.618

High

1026941

PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

1

2

Small-scale

0.618

High

1255562

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1433899

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1435659

WDR26
WD repeat-containing protein 26

1

18

High-throughput

0.618

High

872751

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.611

High

977161

YPEL5
Protein yippee-like 5

2

4

High-throughput

0.611

High

1115063

CUL4A
Cullin-4A

2

20

Small-scale

0.611

High

1391441

RMD5B
E3 ubiquitin-protein transferase RMND5B

2

10

High-throughput

0.611

High

567985

PRG2
Bone marrow proteoglycan

3

8

High-throughput

0.609

High

1435664

EMIL3
EMILIN-3

2

14

High-throughput

0.601

High

248349

HBP1
HMG box-containing protein 1

2

20

Small-scale

0.595

High

242940

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.584

High

1163759

PTN21
Tyrosine-protein phosphatase non-receptor type 21

2

17

High-throughput

0.584

High

1430503

RM18
Large ribosomal subunit protein uL18m

2

0

High-throughput

0.576

High

1181500

EMAL3
Echinoderm microtubule-associated protein-like 3

1

18

High-throughput

0.575

High

1410137

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

19

Small-scale

0.575

High

1435675

COR2B
Coronin-2B

1

18

High-throughput

0.575

High

1013340

HTRA4
Serine protease HTRA4

2

1

High-throughput

0.574

High

1395078

JPH4
Junctophilin-4

2

2

High-throughput

0.574

High

1435678

PRG3
Proteoglycan 3

2

4

High-throughput

0.574

High

1110084

HDAC1
Histone deacetylase 1

2

20

High-throughput

0.571

High

1384268

SH3K1
SH3 domain-containing kinase-binding protein 1

2

10

High-throughput

0.571

High

216818

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.536

High

244282

NUAK1
NUAK family SNF1-like kinase 1

1

3

High-throughput

0.536

High

253454

CST8
Cystatin-8

1

2

High-throughput

0.536

High

270274

MTG16
Protein CBFA2T3

1

1

High-throughput

0.536

High

278750

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

1

High-throughput

0.536

High

320776

UBXN7
UBX domain-containing protein 7

1

8

High-throughput

0.536

High

530381

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.536

High

687302

HMGB2
High mobility group protein B2

1

20

High-throughput

0.536

High

729456

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

20

High-throughput

0.536

High

730892

1433S
14-3-3 protein sigma

1

20

High-throughput

0.536

High

732703

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

974048

RUXF
Small nuclear ribonucleoprotein F

1

13

High-throughput

0.536

High

1049790

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1115434

CUL4B
Cullin-4B

1

20

Small-scale

0.536

High

1162244

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

1

High-throughput

0.536

High

1250857

CRDL2
Chordin-like protein 2

1

7

High-throughput

0.536

High

1325084

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

2

High-throughput

0.536

High

1347869

RIN3
Ras and Rab interactor 3

1

8

High-throughput

0.536

High

1386368

FAF2
FAS-associated factor 2

1

8

High-throughput

0.536

High

1391768

AURKB
Aurora kinase B

1

5

High-throughput

0.536

High

1408510

GDF15
Growth/differentiation factor 15

1

7

High-throughput

0.536

High

1435666

CNOT2
CCR4-NOT transcription complex subunit 2

1

2

High-throughput

0.536

High

1435674

FAF1
FAS-associated factor 1

1

8

High-throughput

0.536

High

1435676

BAIP2
BAR/IMD domain-containing adapter protein 2

1

11

High-throughput

0.536

High

1435677

E41L3
Band 4.1-like protein 3

1

11

High-throughput

0.536

High

831439

CCNF
Cyclin-F

1

7

High-throughput

0.515

High

1402423

HPLN3
Hyaluronan and proteoglycan link protein 3

1

3

High-throughput

0.514

High

169317

LECT2
Leukocyte cell-derived chemotaxin-2

1

0

High-throughput

0.513

High

721738

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

863430

GLYG
Glycogenin-1

1

0

High-throughput

0.513

High

1359751

NEUR4
Sialidase-4

1

0

High-throughput

0.513

High

1389204

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

1435667

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.513

High

1435679

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.513

High

1161217

MK06
Mitogen-activated protein kinase 6

1

8

High-throughput

0.508

High

139081

LAD1
Ladinin-1

1

4

High-throughput

0.489

High

409610

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

3

High-throughput

0.489

High

852318

MMP13
Collagenase 3

1

2

High-throughput

0.489

High

1179859

INSY1
Inhibitory synaptic factor 1

1

2

High-throughput

0.489

High

1393541

MR1L1
MORF4 family-associated protein 1-like 1

1

2

High-throughput

0.489

High

1435662

SPON1
Spondin-1

1

2

High-throughput

0.489

High

1435669

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

1

High-throughput

0.489

High

246953

KDM1A
Lysine-specific histone demethylase 1A

1

10

High-throughput

0.479

High

260460

BRD4
Bromodomain-containing protein 4

1

19

High-throughput

0.479

High

294332

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.479

High

342325

BRD1
Bromodomain-containing protein 1

1

11

High-throughput

0.479

High

350136

SNAI1
Zinc finger protein SNAI1

1

6

High-throughput

0.479

High

363867

EGFR
Epidermal growth factor receptor

1

9

High-throughput

0.479

High

412621

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.479

High

447452

NPM
Nucleophosmin

1

9

High-throughput

0.479

High

508636

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

12

High-throughput

0.479

High

541687

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.479

High

637736

FLNA
Filamin-A

1

17

High-throughput

0.479

High

641259

FGFR2
Fibroblast growth factor receptor 2

1

14

High-throughput

0.479

High

699859

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

8

Small-scale

0.479

High

731621

STIP1
Stress-induced-phosphoprotein 1

1

17

High-throughput

0.479

High

912608

GDIR1
Rho GDP-dissociation inhibitor 1

1

1

Small-scale

0.479

High

956007

RAB8A
Ras-related protein Rab-8A

1

5

High-throughput

0.479

High

965245

WDR5
WD repeat-containing protein 5

1

18

Small-scale

0.479

High

1045772

TF65
Transcription factor p65

1

9

High-throughput

0.479

High

1049001

REL
Proto-oncogene c-Rel

1

11

High-throughput

0.479

High

1089017

TP53B
TP53-binding protein 1

1

9

High-throughput

0.479

High

1092245

NFX1
Transcriptional repressor NF-X1

1

7

High-throughput

0.479

High

1096502

PAK1
Serine/threonine-protein kinase PAK 1

1

10

Small-scale

0.479

High

1100387

TIF1B
Transcription intermediary factor 1-beta

1

17

Small-scale

0.479

High

1106379

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

9

High-throughput

0.479

High

1114314

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1116019

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

16

High-throughput

0.479

High

1121337

TRI14
Tripartite motif-containing protein 14

1

10

High-throughput

0.479

High

1129749

MDC1
Mediator of DNA damage checkpoint protein 1

1

20

High-throughput

0.479

High

1135816

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.479

High

1145374

RNPS1
RNA-binding protein with serine-rich domain 1

1

12

High-throughput

0.479

High

1152044

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

14

High-throughput

0.479

High

1272884

RFIP2
Rab11 family-interacting protein 2

1

9

Small-scale

0.479

High

1280503

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.479

High

1288584

ZN598
E3 ubiquitin-protein ligase ZNF598

1

14

High-throughput

0.479

High

1364596

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1367284

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1384438

PF21A
PHD finger protein 21A

1

20

High-throughput

0.479

High

1390539

CDCA5
Sororin

1

1

High-throughput

0.479

High

1396812

SNX27
Sorting nexin-27

1

7

High-throughput

0.479

High

1397430

CI072
Guanine nucleotide exchange factor C9orf72

1

4

High-throughput

0.479

High

1406776

BARD1
BRCA1-associated RING domain protein 1

1

15

High-throughput

0.479

High

1407468

TS101
Tumor susceptibility gene 101 protein

1

2

Small-scale

0.479

High

1407878

ANM1
Protein arginine N-methyltransferase 1

1

13

High-throughput

0.479

High

1435289

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

1435661

PRD16
Histone-lysine N-methyltransferase PRDM16

1

3

High-throughput

0.479

High

1435668

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1435672

RCOR1
REST corepressor 1

1

14

High-throughput

0.479

High

257504

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

1404404

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.457

High

1435663

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

1435671

TNIK
TRAF2 and NCK-interacting protein kinase

1

14

High-throughput

0.457

High

245005

KATIP
Katanin-interacting protein

1

1

High-throughput

0.445

High

396956

ESR1
Estrogen receptor

1

20

High-throughput

0.445

High

639168

SYT1
Synaptotagmin-1

1

2

High-throughput

0.445

High

664904

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

1

High-throughput

0.445

High

1103380

CTBP1
C-terminal-binding protein 1

1

11

High-throughput

0.445

High

1209664

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

11

High-throughput

0.445

High

1220505

BTBD8
BTB/POZ domain-containing protein 8

1

12

High-throughput

0.445

High

1315553

ULK2
Serine/threonine-protein kinase ULK2

1

7

High-throughput

0.445

High

106661

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

460874

CATB
Cathepsin B

1

3

High-throughput

0.437

High

648677

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.437

High

650417

FGFR3
Fibroblast growth factor receptor 3

1

13

High-throughput

0.437

High

1243904

SG11A
Sperm-associated antigen 11A

1

1

High-throughput

0.437

High

87540

OSCRI
SCRIB overlapping open reading frame protein

1

3

High-throughput

0.407

High

516124

CT456
Cancer/testis antigen family 45 member A6

1

4

High-throughput

0.407

High

1064640

SG11B
Sperm-associated antigen 11B

1

1

High-throughput

0.407

High

1331856

SYT2
Synaptotagmin-2

1

2

High-throughput

0.407

High

561388

TDGF1
Protein Cripto

3

0

High-throughput

0.347

High

1380537

PIGT
GPI-anchor transamidase component PIGT

3

0

High-throughput

0.345

High

1392993

CC120
Coiled-coil domain-containing protein 120

3

0

High-throughput

0.345

High

1435680

INSL6
Insulin-like peptide INSL6

3

0

High-throughput

0.345

High

562761

BMP1
Bone morphogenetic protein 1

2

0

High-throughput

0.328

High

316691

LY6H
Lymphocyte antigen 6H

1

0

High-throughput

0.279

Low

377294

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

0

High-throughput

0.279

Low

477344

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.279

Low

652675

GNLY
Granulysin

1

0

High-throughput

0.279

Low

683753

PTX3
Pentraxin-related protein PTX3

1

0

High-throughput

0.279

Low

1206432

EFHC2
EF-hand domain-containing family member C2

1

0

High-throughput

0.279

Low

1428798

WN10A
Protein Wnt-10a

1

0

High-throughput

0.279

Low

947054

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

615198

PACA
Pituitary adenylate cyclase-activating polypeptide

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025