Protein: TA2R
Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor)

Gene: TA2R, TBXA2R
Organism: Homo sapiens
Interactions: 66
UniProt ID: P21731

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0004961 - thromboxane A2 receptor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005886 - plasma membrane
GO:0006939 - smooth muscle contraction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

640498

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

8

20

Small-scale

0.963

High

640487

TA2R
Thromboxane A2 receptor

7

17

Small-scale

0.956

High

640512

GNA13
Guanine nucleotide-binding protein subunit alpha-13

5

20

Small-scale

0.909

High

640495

PI2R
Prostacyclin receptor

3

17

Small-scale

0.840

High

603161

KPCA
Protein kinase C alpha type

2

4

Small-scale

0.778

High

640491

GNA11
Guanine nucleotide-binding protein subunit alpha-11

2

20

Small-scale

0.754

High

640538

GHRL
Appetite-regulating hormone

1

2

Small-scale

0.724

High

640493

GRK5
G protein-coupled receptor kinase 5

1

20

Small-scale

0.710

High

640511

AAMP
Angio-associated migratory cell protein

1

0

Small-scale

0.702

High

640494

BMR1A
Bone morphogenetic protein receptor type-1A

1

6

High-throughput

0.691

High

640506

RACK1
Small ribosomal subunit protein RACK1

1

2

Small-scale

0.662

High

418593

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

20

Small-scale

0.647

High

640496

GRK6
G protein-coupled receptor kinase 6

1

20

Small-scale

0.647

High

640504

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

20

Small-scale

0.647

High

640509

KCMA1
Calcium-activated potassium channel subunit alpha-1

2

3

Small-scale

0.646

High

400276

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

8

Small-scale

0.618

High

640492

ARRB2
Beta-arrestin-2

1

17

Small-scale

0.618

High

640508

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

20

Small-scale

0.618

High

640503

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

2

4

Small-scale

0.602

High

640519

FTM
Protein fantom

1

1

Small-scale

0.573

High

640501

PSME3
Proteasome activator complex subunit 3

2

1

Small-scale

0.565

High

640525

VRK2
Serine/threonine-protein kinase VRK2

1

2

High-throughput

0.555

High

255978

S19A2
Thiamine transporter 1

1

3

High-throughput

0.536

High

419959

B3A2
Anion exchange protein 2

1

3

High-throughput

0.536

High

541336

FGFR1
Fibroblast growth factor receptor 1

1

7

High-throughput

0.536

High

640489

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

5

High-throughput

0.536

High

640518

S27A3
Long-chain fatty acid transport protein 3

1

2

High-throughput

0.536

High

640510

PRDX4
Peroxiredoxin-4

1

2

Small-scale

0.535

High

640505

1433Z
14-3-3 protein zeta/delta

1

8

Small-scale

0.523

High

640529

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

640502

RB11A
Ras-related protein Rab-11A

1

2

Small-scale

0.512

High

640500

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

2

Small-scale

0.501

High

72651

UPK3L
Uroplakin-3b-like protein 1

1

1

High-throughput

0.489

High

295906

SC5D
Lathosterol oxidase

1

1

High-throughput

0.489

High

640515

LRC10
Leucine-rich repeat-containing protein 10

1

9

High-throughput

0.489

High

640521

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

8

High-throughput

0.489

High

640524

RETR3
Reticulophagy regulator 3

1

1

High-throughput

0.489

High

640526

ZDH17
Palmitoyltransferase ZDHHC17

1

5

High-throughput

0.489

High

640531

GLMN
Glomulin

1

2

High-throughput

0.489

High

640534

TM186
Transmembrane protein 186

1

1

High-throughput

0.489

High

640536

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

7

High-throughput

0.489

High

640537

NFIP2
NEDD4 family-interacting protein 2

1

5

High-throughput

0.489

High

640539

KDIS
Kinase D-interacting substrate of 220 kDa

1

2

High-throughput

0.489

High

640490

CXB2
Gap junction beta-2 protein

1

9

High-throughput

0.481

High

640499

EMP1
Epithelial membrane protein 1

1

4

High-throughput

0.481

High

640516

M4A13
Membrane-spanning 4-domains subfamily A member 13

1

1

High-throughput

0.481

High

640520

MFSD5
Molybdate-anion transporter

1

2

High-throughput

0.481

High

640527

S41A1
Solute carrier family 41 member 1

1

4

High-throughput

0.481

High

640533

PAQR1
Adiponectin receptor protein 1

1

1

High-throughput

0.481

High

640540

NOX1
NADPH oxidase 1

1

1

High-throughput

0.481

High

624474

WT1
Wilms tumor protein

1

2

Small-scale

0.479

High

640507

PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

1

3

Small-scale

0.479

High

640514

KCMB1
Calcium-activated potassium channel subunit beta-1

1

0

Small-scale

0.458

High

640517

GASP1
G-protein coupled receptor-associated sorting protein 1

1

8

Small-scale

0.457

High

640497

T4S4
Transmembrane 4 L6 family member 4

1

3

High-throughput

0.439

High

640523

CE046
Uncharacterized protein C5orf46

1

1

High-throughput

0.439

High

640528

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

1

High-throughput

0.439

High

640532

S35B4
Nucleotide sugar transporter SLC35B4

1

2

High-throughput

0.439

High

640535

ZDH15
Palmitoyltransferase ZDHHC15

1

2

High-throughput

0.439

High

640513

HIC1
Hypermethylated in cancer 1 protein

1

2

Small-scale

0.437

High

640522

PDXD2
Putative pyridoxal-dependent decarboxylase domain-containing protein 2

1

4

High-throughput

0.407

High

165257

PSA7
Proteasome subunit alpha type-7

2

0

Small-scale

0.323

High

640488

NDKB
Nucleoside diphosphate kinase B

1

0

Small-scale

0.299

High

640530

WDR36
WD repeat-containing protein 36

1

0

Small-scale

0.299

High

186242

SIVA
Apoptosis regulatory protein Siva

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025