Protein: TY3H
Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH)

Gene: TY3H, TH
Organism: Homo sapiens
Interactions: 33
UniProt ID: P07101

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001963 - synaptic transmission, dopaminergic
GO:0003007 - heart morphogenesis
GO:0004511 - tyrosine 3-monooxygenase activity
GO:0005506 - iron ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

450293

TY3H
Tyrosine 3-monooxygenase

2

3

High-throughput

0.794

High

450294

NFIC
Nuclear factor 1 C-type

4

0

High-throughput

0.669

High

450303

1433Z
14-3-3 protein zeta/delta

3

5

Small-scale

0.633

High

450320

DJC12
DnaJ homolog subfamily C member 12

2

3

High-throughput

0.628

High

213772

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

0

High-throughput

0.602

High

450321

TAOK2
Serine/threonine-protein kinase TAO2

2

0

High-throughput

0.602

High

297736

PIAS2
E3 SUMO-protein ligase PIAS2

2

0

High-throughput

0.580

High

450299

RABP1
Cellular retinoic acid-binding protein 1

2

0

High-throughput

0.580

High

450301

HNRPK
Heterogeneous nuclear ribonucleoprotein K

2

0

High-throughput

0.580

High

450309

ZN569
Zinc finger protein 569

2

0

High-throughput

0.580

High

450316

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

450319

TSYL4
Testis-specific Y-encoded-like protein 4

2

0

High-throughput

0.580

High

450314

ZBT34
Zinc finger and BTB domain-containing protein 34

2

1

High-throughput

0.574

High

450307

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.513

High

450297

MK03
Mitogen-activated protein kinase 3

1

2

Small-scale

0.501

High

450298

MK01
Mitogen-activated protein kinase 1

1

2

Small-scale

0.501

High

450308

TYSD1
Peroxisomal leader peptide-processing protease

1

0

Small-scale

0.480

High

450296

1433T
14-3-3 protein theta

1

5

Small-scale

0.479

High

450304

CUL3
Cullin-3

1

1

High-throughput

0.479

High

450305

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

450306

EEA1
Early endosome antigen 1

1

1

High-throughput

0.479

High

450302

1433G
14-3-3 protein gamma

1

5

Small-scale

0.445

High

450300

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

450315

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

450310

MTFR2
Mitochondrial fission regulator 2

2

0

High-throughput

0.328

High

450311

KDM3B
Lysine-specific demethylase 3B

2

0

High-throughput

0.328

High

450313

RELL1
RELT-like protein 1

2

0

High-throughput

0.328

High

91594

UMAD1
UBAP1-MVB12-associated

2

0

High-throughput

0.316

High

450295

RBY1A
RNA-binding motif protein, Y chromosome, family 1 member A1

2

0

High-throughput

0.316

High

450318

PUF60
Poly(U)-binding-splicing factor PUF60

2

0

High-throughput

0.316

High

450312

DAAM2
Disheveled-associated activator of morphogenesis 2

1

0

High-throughput

0.251

Low

450317

BAHC1
BAH and coiled-coil domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025