Protein: UBP49
Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49)

Gene: UBP49, USP49
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q70CQ1

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1173829

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

2

14

Small-scale

0.776

High

1034908

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

4

4

Small-scale

0.699

High

863471

COPA
Coatomer subunit alpha

1

5

High-throughput

0.665

High

171148

CETN3
Centrin-3

3

9

Small-scale

0.662

High

1173814

STING
Stimulator of interferon genes protein

2

6

Small-scale

0.624

High

781563

CETN2
Centrin-2

2

7

High-throughput

0.621

High

907074

PRS8
26S proteasome regulatory subunit 8

1

7

Small-scale

0.618

High

386975

P53
Cellular tumor antigen p53

1

5

Small-scale

0.561

High

1157010

ZN774
Zinc finger protein 774

2

1

High-throughput

0.553

High

166954

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

6

High-throughput

0.515

High

176221

PPM1G
Protein phosphatase 1G

1

3

High-throughput

0.515

High

304222

UBR5
E3 ubiquitin-protein ligase UBR5

1

12

High-throughput

0.515

High

312306

IPO7
Importin-7

1

2

High-throughput

0.515

High

568712

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

9

High-throughput

0.515

High

858641

PPP5
Serine/threonine-protein phosphatase 5

1

5

High-throughput

0.515

High

1040594

KRR1
KRR1 small subunit processome component homolog

1

3

High-throughput

0.515

High

1055582

MCM6
DNA replication licensing factor MCM6

1

5

High-throughput

0.515

High

1061762

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

9

High-throughput

0.515

High

1125997

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

4

High-throughput

0.515

High

1173813

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

11

High-throughput

0.515

High

1173816

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

6

High-throughput

0.515

High

1173822

STALP
AMSH-like protease

1

1

High-throughput

0.515

High

1173823

IPO9
Importin-9

1

4

High-throughput

0.515

High

1173827

NUP85
Nuclear pore complex protein Nup85

1

1

High-throughput

0.515

High

1173836

DICER
Endoribonuclease Dicer

1

8

High-throughput

0.515

High

1087213

H2B2E
Histone H2B type 2-E

1

20

Small-scale

0.501

High

789856

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.493

High

1081682

PDCD2
Programmed cell death protein 2

1

0

High-throughput

0.493

High

1173817

SHCBP
SHC SH2 domain-binding protein 1

1

0

High-throughput

0.493

High

1173819

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.493

High

1173835

TRI35
E3 ubiquitin-protein ligase TRIM35

1

9

High-throughput

0.481

High

73152

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

2

High-throughput

0.479

High

259950

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

2

High-throughput

0.479

High

377422

GCR
Glucocorticoid receptor

1

12

Small-scale

0.479

High

431988

HS90A
Heat shock protein HSP 90-alpha

1

4

High-throughput

0.479

High

472709

FBSP1
F-box/SPRY domain-containing protein 1

1

12

Small-scale

0.479

High

555516

H2AX
Histone H2AX

1

17

Small-scale

0.479

High

658628

MSX1
Homeobox protein MSX-1

1

6

Small-scale

0.479

High

659294

DUS1
Dual specificity protein phosphatase 1

1

3

Small-scale

0.479

High

717174

CTNB1
Catenin beta-1

1

14

Small-scale

0.479

High

977899

HSF2
Heat shock factor protein 2

1

2

High-throughput

0.479

High

1069392

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.479

High

1080057

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

Small-scale

0.479

High

1173815

NUDC3
NudC domain-containing protein 3

1

2

High-throughput

0.479

High

1173820

HS105
Heat shock protein 105 kDa

1

6

Small-scale

0.479

High

1173826

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.479

High

1173832

ABC3G
DNA dC->dU-editing enzyme APOBEC-3G

1

1

Small-scale

0.479

High

1173833

CHIP
E3 ubiquitin-protein ligase CHIP

1

7

High-throughput

0.479

High

1173837

RUVB1
RuvB-like 1

1

4

Small-scale

0.479

High

1173840

NS1BP
Influenza virus NS1A-binding protein

1

6

Small-scale

0.479

High

257190

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

6

High-throughput

0.470

High

390313

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.470

High

684830

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.470

High

778194

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.470

High

1016728

CETN1
Centrin-1

1

7

High-throughput

0.470

High

1173834

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

4

High-throughput

0.470

High

878425

PAX9
Paired box protein Pax-9

1

0

Small-scale

0.458

High

1082841

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.458

High

1173831

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1173839

ZHX2
Zinc fingers and homeoboxes protein 2

1

0

Small-scale

0.458

High

1173828

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

13

High-throughput

0.439

High

323852

BAG2
BAG family molecular chaperone regulator 2

1

1

Small-scale

0.437

High

1162503

Q6PK50
Heat shock protein HSP 90-beta

1

6

High-throughput

0.437

High

1173821

Q96BE0
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.437

High

1173824

WRIP1
ATPase WRNIP1

1

4

Small-scale

0.437

High

1173825

Q9BPW0
Serine/threonine-protein phosphatase

1

5

High-throughput

0.437

High

1173830

Q9HAV2
Heat shock transcription factor 1

1

1

High-throughput

0.437

High

796854

NAMPT
Nicotinamide phosphoribosyltransferase

2

0

High-throughput

0.316

High

1173818

PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

2

0

High-throughput

0.316

High

1089299

IMPG1
Interphotoreceptor matrix proteoglycan 1

1

0

High-throughput

0.279

Low

444283

FA7
Coagulation factor VII

1

0

High-throughput

0.269

Low

1173838

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024