Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: IRF5 (P56477)
Interferon regulatory factor 5 (IRF-5)
Gene: IRF5

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21731497
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRF~IRF, IRF-3~IRF-3
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0032735 - positive regulation of interleukin-12 production
GO:0043065 - positive regulation of apoptotic process
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 424
Mm

1 497
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Service provided by Combinatics, Japan

Last updated: 11Aug2025