Protein: MAVS
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)

Gene: MAVS
Organism: Mus musculus
Interactions: 31
UniProt ID: Q8VCF0

Gene Ontology (top 5):
GO:0002218 - activation of innate immune response
GO:0002230 - positive regulation of defense response to virus by host
GO:0002735 - positive regulation of myeloid dendritic cell cytokine production
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1246271

RIGI
Antiviral innate immune response receptor RIG-I

2

13

Small-scale

0.754

High

1221533

TRAF3
TNF receptor-associated factor 3

4

16

Small-scale

0.687

High

1341658

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

12

Small-scale

0.618

High

1341591

NLRP3
NACHT, LRR and PYD domains-containing protein 3

2

2

Small-scale

0.601

High

1341459

TRI31
E3 ubiquitin-protein ligase TRIM31

2

5

Small-scale

0.584

High

204611

DHX15
ATP-dependent RNA helicase DHX15

1

1

Small-scale

0.479

High

312508

NEMO
NF-kappa-B essential modulator

1

8

Small-scale

0.479

High

811923

TRAF2
TNF receptor-associated factor 2

1

16

Small-scale

0.479

High

999818

TRAF5
TNF receptor-associated factor 5

1

18

Small-scale

0.479

High

999875

TRAF6
TNF receptor-associated factor 6

1

17

Small-scale

0.479

High

1000258

TANK
TRAF family member-associated NF-kappa-B activator

1

1

Small-scale

0.479

High

1188723

STING
Stimulator of interferon genes protein

1

3

High-throughput

0.479

High

1190391

TAXB1
Tax1-binding protein 1 homolog

1

8

Small-scale

0.479

High

1243982

SARM1
NAD(+) hydrolase SARM1

1

1

Small-scale

0.479

High

1281976

MFN2
Mitofusin-2

1

2

Small-scale

0.479

High

1298170

ITCH
E3 ubiquitin-protein ligase Itchy

1

11

Small-scale

0.479

High

1353880

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

11

Small-scale

0.479

High

1353881

ASC
Apoptosis-associated speck-like protein containing a CARD

1

2

Small-scale

0.479

High

73948

OTUD4
OTU domain-containing protein 4

1

4

Small-scale

0.437

High

607848

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

Small-scale

0.437

High

912282

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

9

Small-scale

0.437

High

988906

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.437

High

1189994

Q3UCL2
E3 ubiquitin-protein ligase TRIM21

1

3

Small-scale

0.437

High

1230534

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

High-throughput

0.437

High

1353883

UBP18
Ubl carboxyl-terminal hydrolase 18

1

11

Small-scale

0.437

High

1353884

EYA4
Protein phosphatase EYA4

1

3

Small-scale

0.437

High

1353885

PSA7
Proteasome subunit alpha type-7

1

2

Small-scale

0.437

High

398790

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

1190006

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

0

Small-scale

0.249

Low

1317477

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low

1353882

B9D1
B9 domain-containing protein 1

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025