Protein: AKTIP
AKT-interacting protein (Ft1) (Fused toes protein homolog)

Gene: AKTIP
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q9H8T0

Gene Ontology (top 5):
GO:0001934 - positive regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0006301 - postreplication repair
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1436475

HOOK1
Protein Hook homolog 1

11

4

Small-scale

0.981

High

1388861

HOOK2
Protein Hook homolog 2

10

4

Small-scale

0.979

High

1291582

HOOK3
Protein Hook homolog 3

8

4

Small-scale

0.972

High

1328727

FHI1B
FHF complex subunit HOOK-interacting protein 1B

6

3

Small-scale

0.946

High

1053461

FHI1A
FHF complex subunit HOOK-interacting protein 1A

5

3

Small-scale

0.920

High

1093429

TRI32
E3 ubiquitin-protein ligase TRIM32

4

20

High-throughput

0.905

High

1436479

TRI35
E3 ubiquitin-protein ligase TRIM35

2

20

High-throughput

0.811

High

783416

TRI23
E3 ubiquitin-protein ligase TRIM23

1

7

High-throughput

0.698

High

1436482

TN13B
Tumor necrosis factor ligand superfamily member 13B

4

0

High-throughput

0.670

High

1364993

TSC1
Hamartin

3

2

High-throughput

0.667

High

334910

IPO7
Importin-7

1

4

Small-scale

0.648

High

1108486

NAB1
NGFI-A-binding protein 1

3

0

High-throughput

0.638

High

1294571

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

20

High-throughput

0.625

High

1351315

DMXL2
DmX-like protein 2

1

8

High-throughput

0.625

High

1340071

ZNRF2
E3 ubiquitin-protein ligase ZNRF2

1

18

Small-scale

0.621

High

508642

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

Small-scale

0.618

High

1436467

AKTIP
AKT-interacting protein

1

16

Small-scale

0.618

High

386241

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

Small-scale

0.561

High

634641

LMNB1
Lamin-B1

1

4

Small-scale

0.561

High

728430

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.561

High

846479

MATR3
Matrin-3

1

1

Small-scale

0.561

High

928553

TERF1
Telomeric repeat-binding factor 1

1

1

Small-scale

0.561

High

1149993

TERF2
Telomeric repeat-binding factor 2

1

1

Small-scale

0.561

High

363870

EGFR
Epidermal growth factor receptor

2

0

Small-scale

0.559

High

921520

PGTB1
Geranylgeranyl transferase type-1 subunit beta

2

1

High-throughput

0.558

High

1104262

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

5

High-throughput

0.553

High

1219957

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

3

High-throughput

0.553

High

1290242

FHI2B
FHF complex subunit HOOK-interacting protein 2B

1

3

High-throughput

0.553

High

165469

RGRF2
Ras-specific guanine nucleotide-releasing factor 2

1

1

High-throughput

0.541

High

214038

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

High-throughput

0.541

High

1436470

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

6

High-throughput

0.541

High

1436477

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

Small-scale

0.529

High

696529

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.518

High

941564

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.518

High

1218013

MYOME
Myomegalin

1

0

High-throughput

0.518

High

1436468

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.518

High

1436480

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.518

High

773784

ACTN2
Alpha-actinin-2

1

1

High-throughput

0.494

High

1122774

DPOA2
DNA polymerase alpha subunit B

1

1

High-throughput

0.494

High

1357759

TRI41
E3 ubiquitin-protein ligase TRIM41

1

20

High-throughput

0.494

High

1024850

VIGLN
Vigilin

1

0

High-throughput

0.493

High

1177644

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.493

High

317258

AL1A2
Retinal dehydrogenase 2

1

1

High-throughput

0.489

High

246140

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.479

High

409086

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

Small-scale

0.479

High

539258

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

3

Small-scale

0.479

High

566042

EF2
Elongation factor 2

1

1

Small-scale

0.479

High

576555

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

2

Small-scale

0.479

High

727968

DNJA1
DnaJ homolog subfamily A member 1

1

1

Small-scale

0.479

High

761518

HS71L
Heat shock 70 kDa protein 1-like

1

2

Small-scale

0.479

High

852854

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

1

Small-scale

0.479

High

888818

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

5

Small-scale

0.479

High

935145

TERA
Transitional endoplasmic reticulum ATPase

1

2

Small-scale

0.479

High

1098673

SBP1
Methanethiol oxidase

1

1

Small-scale

0.479

High

1138642

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

1256837

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

1

1

Small-scale

0.479

High

1291218

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

Small-scale

0.479

High

1436472

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

5

Small-scale

0.479

High

1436476

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

2

Small-scale

0.479

High

1123823

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.470

High

446049

ENOA
Alpha-enolase

1

0

Small-scale

0.458

High

528353

THIO
Thioredoxin

1

0

Small-scale

0.458

High

532975

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.458

High

949441

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

Small-scale

0.458

High

953104

ACTB
Actin, cytoplasmic 1

1

0

Small-scale

0.458

High

969057

PRS8
26S proteasome regulatory subunit 8

1

0

Small-scale

0.458

High

980338

H4
Histone H4

1

0

Small-scale

0.458

High

1008356

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

Small-scale

0.458

High

1058280

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.458

High

1118253

BLMH
Bleomycin hydrolase

1

0

Small-scale

0.458

High

1149678

SURF2
Surfeit locus protein 2

1

0

Small-scale

0.458

High

1310129

MGAP
MAX gene-associated protein

1

0

High-throughput

0.458

High

1399457

SPB12
Serpin B12

1

0

Small-scale

0.458

High

1431579

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

Small-scale

0.458

High

1436483

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

946457

MTPN
Myotrophin

1

6

High-throughput

0.457

High

946533

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.438

High

1392636

CENPN
Centromere protein N

1

0

High-throughput

0.438

High

428518

RLA2
Large ribosomal subunit protein P2

1

1

Small-scale

0.437

High

651878

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

Small-scale

0.437

High

712278

TKT
Transketolase

1

3

Small-scale

0.437

High

829548

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

Small-scale

0.437

High

834534

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.437

High

935989

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

Small-scale

0.437

High

969692

RS15A
Small ribosomal subunit protein uS8

1

2

Small-scale

0.437

High

1042079

LMNB2
Lamin-B2

1

4

Small-scale

0.437

High

1436471

HACD3
Very-long-chain

1

3

Small-scale

0.437

High

1436474

SYLC
Leucine--tRNA ligase, cytoplasmic

1

2

Small-scale

0.437

High

1219546

ANR22
Ankyrin repeat domain-containing protein 22

1

1

High-throughput

0.407

High

1192112

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

2

0

Small-scale

0.313

High

369090

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.282

High

635554

NEBU
Nebulin

1

0

High-throughput

0.282

High

1085836

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.282

High

1164574

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.282

High

1401810

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.282

High

1415351

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.282

High

1436473

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

1322145

SYCE1
Synaptonemal complex central element protein 1

1

0

High-throughput

0.279

Low

1436469

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

0

High-throughput

0.279

Low

213490

CTIF
CBP80/20-dependent translation initiation factor

1

0

High-throughput

0.249

Low

275758

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

Small-scale

0.249

Low

732406

PRDX2
Peroxiredoxin-2

1

0

Small-scale

0.249

Low

1393707

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1403733

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

Small-scale

0.249

Low

1436478

AP4E1
AP-4 complex subunit epsilon-1

1

0

Small-scale

0.249

Low

1436481

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

Small-scale

0.249

Low

1382702

EMID1
EMI domain-containing protein 1

1

0

High-throughput

0.238

Low

1167116

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025