Protein: PMVK
Phosphomevalonate kinase (PMKase) (hPMK) (EC 2.7.4.2)

Gene: PMVK
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q15126

Gene Ontology (top 5):
GO:0004631 - phosphomevalonate kinase activity
GO:0005524 - ATP binding
GO:0005777 - peroxisome
GO:0005829 - cytosol
GO:0006695 - cholesterol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1143020

MBD5
Methyl-CpG-binding domain protein 5

3

0

High-throughput

0.638

High

387835

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

0

High-throughput

0.602

High

708970

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.602

High

1142986

S2535
Solute carrier family 25 member 35

2

1

High-throughput

0.558

High

1036731

DSG1
Desmoglein-1

1

1

High-throughput

0.536

High

1143011

FSD1
Fibronectin type III and SPRY domain-containing protein 1

1

1

High-throughput

0.536

High

132594

UPK1A
Uroplakin-1a

1

0

High-throughput

0.513

High

219176

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.513

High

229231

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.513

High

458691

SAP
Prosaposin

1

0

High-throughput

0.513

High

552969

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

602790

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

724576

S10A7
Protein S100-A7

1

0

High-throughput

0.513

High

730597

1433S
14-3-3 protein sigma

1

0

High-throughput

0.513

High

854069

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

1064430

DSC1
Desmocollin-1

1

0

High-throughput

0.513

High

1118215

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.513

High

1136016

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

1142989

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

1142994

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1143001

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1143004

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.513

High

1143006

UIF
UAP56-interacting factor

1

0

High-throughput

0.513

High

1143007

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.513

High

1143008

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.513

High

1143010

VPS25
Vacuolar protein-sorting-associated protein 25

1

0

High-throughput

0.513

High

1143013

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

1143015

KRA32
Keratin-associated protein 3-2

1

0

High-throughput

0.513

High

1143016

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1143022

HSPB8
Heat shock protein beta-8

1

0

High-throughput

0.513

High

1143023

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

0

High-throughput

0.513

High

276960

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.493

High

431135

LA
Lupus La protein

1

0

High-throughput

0.493

High

1024278

PIPNA
Phosphatidylinositol transfer protein alpha isoform

1

0

High-throughput

0.493

High

1142984

MLF2
Myeloid leukemia factor 2

1

0

High-throughput

0.493

High

1143018

CENPH
Centromere protein H

1

0

High-throughput

0.493

High

165460

RGRF2
Ras-specific guanine nucleotide-releasing factor 2

1

0

High-throughput

0.458

High

418145

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

529828

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.458

High

827791

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.458

High

830773

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

872349

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

998339

H31
Histone H3.1

1

0

High-throughput

0.458

High

1142998

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.458

High

1143014

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1143021

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1142990

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

125469

LEG9
Galectin-9

1

0

High-throughput

0.426

High

142340

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.426

High

231576

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.426

High

619804

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.426

High

1142988

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1142995

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

3

0

High-throughput

0.347

High

1143012

SCNM1
Sodium channel modifier 1

3

0

High-throughput

0.347

High

1143017

S2532
Solute carrier family 25 member 32

3

0

High-throughput

0.347

High

376987

ANF
Natriuretic peptides A

2

0

High-throughput

0.328

High

1142985

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

1142997

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.328

High

1103079

ZN177
Zinc finger protein 177

2

0

High-throughput

0.316

High

1143003

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

74496

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

246234

MABP1
Mitogen-activated protein kinase-binding protein 1

1

0

High-throughput

0.279

Low

261621

CATL2
Cathepsin L2

1

0

High-throughput

0.279

Low

326704

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

351779

LGI1
Leucine-rich glioma-inactivated protein 1

1

0

High-throughput

0.279

Low

724083

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

733354

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

1117941

PKP1
Plakophilin-1

1

0

High-throughput

0.279

Low

1142987

CENPW
Centromere protein W

1

0

High-throughput

0.279

Low

1142992

SETD3
Actin-histidine N-methyltransferase

1

0

High-throughput

0.279

Low

1142993

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

1143000

NKD2
Protein naked cuticle homolog 2

1

0

High-throughput

0.279

Low

1143002

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

1143005

RDH12
Retinol dehydrogenase 12

1

0

High-throughput

0.279

Low

1143009

KCD14
BTB/POZ domain-containing protein KCTD14

1

0

High-throughput

0.279

Low

1143019

GSX1
GS homeobox 1

1

0

High-throughput

0.279

Low

1143024

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

0

High-throughput

0.279

Low

303132

RGS20
Regulator of G-protein signaling 20

1

0

High-throughput

0.269

Low

975581

TBPL1
TATA box-binding protein-like 1

1

0

High-throughput

0.269

Low

1142996

MCPH1
Microcephalin

1

0

Small-scale

0.251

Low

1142991

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1142999

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025