Protein: CYBR1
Plasma membrane ascorbate-dependent reductase CYBRD1 (EC 7.2.1.3) (Cytochrome b reductase 1) (Duodenal cytochrome b) (Ferric-chelate reductase 3)

Gene: CYBR1, CYBRD1
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q53TN4

Gene Ontology (top 5):
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0010039 - response to iron ion
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1087134

STX4
Syntaxin-4

3

4

High-throughput

0.688

High

160277

GOSR2
Golgi SNAP receptor complex member 2

2

1

High-throughput

0.606

High

189604

STX7
Syntaxin-7

2

4

High-throughput

0.606

High

333035

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

3

High-throughput

0.606

High

483919

HMOX1
Heme oxygenase 1

2

2

High-throughput

0.606

High

1050026

PLP2
Proteolipid protein 2

2

1

High-throughput

0.606

High

1125466

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

1

High-throughput

0.606

High

1200532

TMM65
Transmembrane protein 65

2

1

High-throughput

0.606

High

1200542

GIMA5
GTPase IMAP family member 5

2

3

High-throughput

0.606

High

1200549

VAPA
Vesicle-associated membrane protein-associated protein A

2

3

High-throughput

0.606

High

1200550

LPAR3
Lysophosphatidic acid receptor 3

2

2

High-throughput

0.606

High

327290

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.580

High

1200546

TACAN
Transmembrane protein 120A

2

0

High-throughput

0.580

High

1200552

PRAF1
Prenylated Rab acceptor protein 1

2

0

High-throughput

0.580

High

1200533

MIER1
Mesoderm induction early response protein 1

2

1

High-throughput

0.574

High

1200534

MIER2
Mesoderm induction early response protein 2

2

1

High-throughput

0.574

High

1200536

SERP2
Stress-associated endoplasmic reticulum protein 2

2

2

High-throughput

0.553

High

1200544

SC22A
Vesicle-trafficking protein SEC22a

2

1

High-throughput

0.553

High

1200556

SERP1
Stress-associated endoplasmic reticulum protein 1

2

2

High-throughput

0.553

High

1109787

HDAC1
Histone deacetylase 1

1

1

High-throughput

0.536

High

1200537

MY18A
Unconventional myosin-XVIIIa

1

1

High-throughput

0.536

High

1200543

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.536

High

1200545

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

0

Small-scale

0.529

High

280649

PR40A
Pre-mRNA-processing factor 40 homolog A

1

1

High-throughput

0.515

High

239843

PCDH7
Protocadherin-7

1

0

High-throughput

0.513

High

337102

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.513

High

637552

FLNA
Filamin-A

1

0

High-throughput

0.513

High

772837

MYH9
Myosin-9

1

0

High-throughput

0.513

High

862863

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.513

High

901283

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.513

High

958284

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

1102792

UT1
Urea transporter 1

1

0

High-throughput

0.513

High

1200535

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

1200539

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1200551

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

1200555

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

562095

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

1200554

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

1200538

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.489

High

230332

CREB3
Cyclic AMP-responsive element-binding protein 3

1

3

High-throughput

0.481

High

1140377

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1200547

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

385812

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.439

High

331029

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.437

High

1200553

CDYL
Chromodomain Y-like protein

2

0

High-throughput

0.328

High

1160645

DREB
Drebrin

1

0

High-throughput

0.279

Low

1200541

F136A
Protein FAM136A

1

0

High-throughput

0.279

Low

1200540

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.269

Low

937020

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

106058

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1200548

ANLN
Anillin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025