Protein: PLP2
Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein)

Gene: PLP2
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q04941

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0006935 - chemotaxis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

733336

CCR1
C-C chemokine receptor type 1

2

3

Small-scale

0.618

High

138559

CLD5
Claudin-5

2

1

High-throughput

0.606

High

166903

MGST3
Glutathione S-transferase 3, mitochondrial

2

1

High-throughput

0.606

High

188868

TMPS2
Transmembrane protease serine 2

2

1

High-throughput

0.606

High

317109

AQP8
Aquaporin-8

2

1

High-throughput

0.606

High

337721

SGPL1
Sphingosine-1-phosphate lyase 1

2

3

High-throughput

0.606

High

549763

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

2

High-throughput

0.606

High

622047

CD53
Leukocyte surface antigen CD53

2

1

High-throughput

0.606

High

883410

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

1

High-throughput

0.606

High

920560

ARFP2
Arfaptin-2

2

2

High-throughput

0.606

High

926763

VMAT1
Chromaffin granule amine transporter

2

1

High-throughput

0.606

High

1050015

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

2

1

High-throughput

0.606

High

1050022

UT2
Urea transporter 2

2

1

High-throughput

0.606

High

1050026

CYBR1
Plasma membrane ascorbate-dependent reductase CYBRD1

2

1

High-throughput

0.606

High

1050033

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

4

High-throughput

0.606

High

1050034

CPLX4
Complexin-4

2

1

High-throughput

0.606

High

1050035

RETR3
Reticulophagy regulator 3

2

4

High-throughput

0.606

High

1050036

LHPL1
LHFPL tetraspan subfamily member 1 protein

2

2

High-throughput

0.606

High

1050039

DHB11
Estradiol 17-beta-dehydrogenase 11

2

4

High-throughput

0.606

High

1050040

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

2

High-throughput

0.606

High

1050041

FNDC9
Fibronectin type III domain-containing protein 9

2

1

High-throughput

0.606

High

1050042

GP151
G-protein coupled receptor 151

2

2

High-throughput

0.606

High

1050044

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.606

High

1050046

AQP3
Aquaporin-3

2

1

High-throughput

0.606

High

1050048

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

3

High-throughput

0.606

High

1050050

DNJC1
DnaJ homolog subfamily C member 1

2

2

High-throughput

0.606

High

1050054

RNF5
E3 ubiquitin-protein ligase RNF5

2

1

High-throughput

0.606

High

1050060

REEP4
Receptor expression-enhancing protein 4

2

5

High-throughput

0.606

High

1050062

CERS4
Ceramide synthase 4

2

1

High-throughput

0.606

High

1050063

LRC4C
Leucine-rich repeat-containing protein 4C

2

2

High-throughput

0.606

High

1050065

SAR1A
Small COPII coat GTPase SAR1A

2

1

High-throughput

0.606

High

1050068

SCN3B
Sodium channel regulatory subunit beta-3

2

1

High-throughput

0.606

High

1050069

ELOV5
Very long chain fatty acid elongase 5

2

3

High-throughput

0.606

High

1050073

NDRG4
Protein NDRG4

2

1

High-throughput

0.606

High

1050074

TMX2
Thioredoxin-related transmembrane protein 2

2

1

High-throughput

0.606

High

1050037

LACC1
Purine nucleoside phosphorylase LACC1

2

0

High-throughput

0.585

High

161355

PTGES
Prostaglandin E synthase

2

0

High-throughput

0.580

High

455967

ASGR2
Asialoglycoprotein receptor 2

2

0

High-throughput

0.580

High

580760

PVR
Poliovirus receptor

2

0

High-throughput

0.580

High

592717

LEUK
Leukosialin

2

0

High-throughput

0.580

High

652839

EVI2A
Protein EVI2A

2

0

High-throughput

0.580

High

943438

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

2

0

High-throughput

0.580

High

1050021

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1050047

FATE1
Fetal and adult testis-expressed transcript protein

2

0

High-throughput

0.580

High

1050049

T4S19
Transmembrane 4 L6 family member 19

2

0

High-throughput

0.580

High

1050051

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.580

High

1050052

MYCT
Proton myo-inositol cotransporter

2

0

High-throughput

0.580

High

1050055

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.580

High

1050058

CRUM3
Protein crumbs homolog 3

2

0

High-throughput

0.580

High

1050061

PACC1
Proton-activated chloride channel

2

0

High-throughput

0.580

High

1050067

TMM51
Transmembrane protein 51

2

0

High-throughput

0.580

High

91647

HSBPL
Heat shock factor-binding protein 1-like protein 1

2

1

High-throughput

0.553

High

1050017

BIK
Bcl-2-interacting killer

2

2

High-throughput

0.553

High

1050028

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

1050045

THAP4
Peroxynitrite isomerase THAP4

2

2

High-throughput

0.553

High

1050059

CIA2A
Cytosolic iron-sulfur assembly component 2A

2

1

High-throughput

0.553

High

1050064

S35C2
Solute carrier family 35 member C2

2

1

High-throughput

0.553

High

1050066

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

1050070

SPG21
Maspardin

2

3

High-throughput

0.553

High

1050038

KASH5
Protein KASH5

1

1

High-throughput

0.523

High

755475

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.513

High

1050053

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

1050071

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.513

High

932728

EMP3
Epithelial membrane protein 3

1

1

Small-scale

0.506

High

1050043

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

1

High-throughput

0.489

High

590272

MUC1
Mucin-1

1

1

High-throughput

0.481

High

832622

AQP2
Aquaporin-2

1

4

Small-scale

0.481

High

1050024

SOAT
Sodium-dependent organic anion transporter

1

2

High-throughput

0.481

High

1050029

TMM31
Transmembrane protein 31

1

1

High-throughput

0.481

High

1050014

PLP2
Proteolipid protein 2

1

1

Small-scale

0.479

High

718687

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.460

High

1050056

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

1050072

CLN8
Protein CLN8

1

0

Small-scale

0.460

High

1050076

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.460

High

176969

CE290
Centrosomal protein of 290 kDa

1

0

High-throughput

0.458

High

418080

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

822627

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

985625

RL11
Large ribosomal subunit protein uL5

1

0

Small-scale

0.458

High

385673

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

3

High-throughput

0.439

High

1050019

AQP6
Aquaporin-6

1

4

High-throughput

0.439

High

1050025

AR13B
ADP-ribosylation factor-like protein 13B

1

2

High-throughput

0.439

High

217319

PROM1
Prominin-1

1

0

Small-scale

0.438

High

1050032

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1050057

TMM79
Transmembrane protein 79

2

0

High-throughput

0.327

High

617502

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

2

0

High-throughput

0.316

High

1050016

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

1050031

SYDM
Aspartate--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

327581

ELP1
Elongator complex protein 1

1

0

High-throughput

0.265

Low

407805

SHBG
Sex hormone-binding globulin

1

0

Small-scale

0.251

Low

872237

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

1004476

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1050020

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.249

Low

1050023

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1050027

SGO2
Shugoshin 2

1

0

High-throughput

0.249

Low

1050075

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.249

Low

1050018

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.232

Low

1050030

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025