Protein: HSH2D
Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X)

Gene: HSH2D
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q96JZ2

Gene Ontology (top 5):
GO:0002903 - negative regulation of B cell apoptotic process
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1060803

ACK1
Activated CDC42 kinase 1

3

20

Small-scale

0.861

High

855727

CRK
Adapter molecule crk

2

20

High-throughput

0.767

High

1364854

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.767

High

456115

FES
Tyrosine-protein kinase Fes/Fps

1

20

Small-scale

0.740

High

472117

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

532099

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

363720

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

411004

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

641653

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

1145767

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

1103518

MPP3
MAGUK p55 subfamily member 3

1

18

High-throughput

0.625

High

1395585

TS101
Tumor susceptibility gene 101 protein

2

2

High-throughput

0.606

High

1364966

TSC1
Hamartin

2

20

High-throughput

0.594

High

1395584

RET7
Retinoid-binding protein 7

2

4

High-throughput

0.594

High

1395586

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

2

20

High-throughput

0.594

High

1395587

LDH6B
L-lactate dehydrogenase A-like 6B

2

3

High-throughput

0.594

High

1347277

OLIG1
Oligodendrocyte transcription factor 1

2

8

High-throughput

0.576

High

520294

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

1106498

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.536

High

1314583

MKX
Homeobox protein Mohawk

1

2

High-throughput

0.479

High

114571

H0YKC7
Mohawk homeobox

1

2

High-throughput

0.445

High

295421

CNMD
Leukocyte cell-derived chemotaxin 1

2

0

High-throughput

0.310

High

338168

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.269

Low

1313636

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025