Protein: ZIC3
Zinc finger protein ZIC 3 (Zinc finger protein 203) (Zinc finger protein of the cerebellum 3)

Gene: ZIC3
Organism: Homo sapiens
Interactions: 24
UniProt ID: O60481

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 - skeletal system development
GO:0001840 - neural plate development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

249333

GLI3
Transcriptional activator GLI3

2

20

Small-scale

0.778

High

249330

P53
Cellular tumor antigen p53

1

5

High-throughput

0.527

High

249335

CTNB1
Catenin beta-1

1

6

High-throughput

0.527

High

249344

TWST1
Twist-related protein 1

1

5

High-throughput

0.527

High

249337

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

0

High-throughput

0.518

High

249334

SRF
Serum response factor

1

1

Small-scale

0.501

High

123520

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.500

High

227732

MYO1B
Unconventional myosin-Ib

1

4

High-throughput

0.500

High

249329

MYO1D
Unconventional myosin-Id

1

3

High-throughput

0.500

High

249336

MYH10
Myosin-10

1

2

High-throughput

0.500

High

249342

FHL1
Four and a half LIM domains protein 1

1

17

High-throughput

0.500

High

249346

MYH14
Myosin-14

1

2

High-throughput

0.500

High

249347

RBM33
RNA-binding protein 33

1

3

High-throughput

0.500

High

249350

MYO6
Unconventional myosin-VI

1

2

High-throughput

0.500

High

249341

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.479

High

249345

DREB
Drebrin

1

0

High-throughput

0.479

High

249339

RNF4
E3 ubiquitin-protein ligase RNF4

1

17

High-throughput

0.479

High

249340

PO5F1
POU domain, class 5, transcription factor 1

1

15

High-throughput

0.479

High

249349

NANOG
Homeobox protein NANOG

1

9

High-throughput

0.479

High

249348

MESP1
Mesoderm posterior protein 1

1

0

Small-scale

0.460

High

249331

TPM3
Tropomyosin alpha-3 chain

1

4

High-throughput

0.457

High

249332

TPM1
Tropomyosin alpha-1 chain

1

4

High-throughput

0.457

High

249338

TPM4
Tropomyosin alpha-4 chain

1

4

High-throughput

0.457

High

249343

FLOT2
Flotillin-2

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025