Protein: FANCG
Fanconi anemia group G protein (Protein FACG) (DNA repair protein XRCC9)

Gene: FANCG
Organism: Homo sapiens
Interactions: 137
UniProt ID: O15287

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001541 - ovarian follicle development
GO:0003684 - damaged DNA binding
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

185126

FANCA
Fanconi anemia group A protein

54

2

Small-scale

0.772

High

185180

FANCC
Fanconi anemia group C protein

9

1

Small-scale

0.745

High

185238

FANCF
Fanconi anemia group F protein

10

0

Small-scale

0.725

High

185213

FANCM
Fanconi anemia group M protein

5

2

Small-scale

0.709

High

185244

FANCL
E3 ubiquitin-protein ligase FANCL

5

1

Small-scale

0.702

High

185236

FANCE
Fanconi anemia group E protein

5

0

Small-scale

0.683

High

185174

BRCA2
Breast cancer type 2 susceptibility protein

4

0

Small-scale

0.669

High

185202

FAP20
Fanconi anemia core complex-associated protein 20

4

0

Small-scale

0.664

High

185221

FANCB
Fanconi anemia group B protein

4

0

Small-scale

0.653

High

185125

FANCG
Fanconi anemia group G protein

4

0

Small-scale

0.642

High

185128

XRCC3
DNA repair protein XRCC3

3

0

Small-scale

0.633

High

185193

SPTN1
Spectrin alpha chain, non-erythrocytic 1

2

1

Small-scale

0.626

High

185217

USBP1
Harmonin-binding protein USHBP1

3

1

High-throughput

0.610

High

185146

K1C19
Keratin, type I cytoskeletal 19

2

2

High-throughput

0.608

High

185186

FP100
Fanconi anemia core complex-associated protein 100

3

0

Small-scale

0.606

High

185135

ZBED1
E3 SUMO-protein ligase ZBED1

2

0

High-throughput

0.605

High

185127

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

2

0

High-throughput

0.602

High

185147

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

0

High-throughput

0.602

High

185154

DPEP1
Dipeptidase 1

2

0

High-throughput

0.602

High

185235

CSTFT
Cleavage stimulation factor subunit 2 tau variant

2

0

High-throughput

0.602

High

185194

HES1
Transcription factor HES-1

2

0

Small-scale

0.593

High

185218

TPRX1
Tetra-peptide repeat homeobox protein 1

2

0

High-throughput

0.580

High

185149

K1C13
Keratin, type I cytoskeletal 13

1

1

High-throughput

0.560

High

70855

CENPX
Centromere protein X

2

0

Small-scale

0.559

High

185214

CENPS
Centromere protein S

2

0

Small-scale

0.559

High

185234

FACD2
Fanconi anemia group D2 protein

2

0

Small-scale

0.559

High

185139

CP2E1
Cytochrome P450 2E1

2

1

Small-scale

0.556

High

185229

UIMC1
BRCA1-A complex subunit RAP80

1

0

Small-scale

0.554

High

185246

DOK5
Docking protein 5

2

0

High-throughput

0.551

High

185188

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

1

High-throughput

0.549

High

185172

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

0

Small-scale

0.537

High

185152

GATA1
Erythroid transcription factor

1

0

High-throughput

0.536

High

185201

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.536

High

185247

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.536

High

185249

IKZF3
Zinc finger protein Aiolos

1

0

High-throughput

0.536

High

185251

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

0

High-throughput

0.536

High

185160

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

185164

SPB3
Serpin B3

1

1

High-throughput

0.536

High

185242

KIF15
Kinesin-like protein KIF15

1

1

High-throughput

0.536

High

185142

CAN1
Calpain-1 catalytic subunit

1

0

Small-scale

0.529

High

185143

ERCC1
DNA excision repair protein ERCC-1

1

0

Small-scale

0.529

High

185165

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

0

Small-scale

0.529

High

185190

CTBP1
C-terminal-binding protein 1

1

0

Small-scale

0.529

High

185182

GABP1
GA-binding protein subunit beta-1

1

0

High-throughput

0.518

High

185211

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.518

High

185144

VIME
Vimentin

1

1

High-throughput

0.515

High

185150

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.515

High

185141

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.513

High

185170

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.513

High

185204

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

185228

GSDMA
Gasdermin-A

1

0

High-throughput

0.513

High

185231

FAP24
Fanconi anemia core complex-associated protein 24

1

0

Small-scale

0.513

High

167196

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

185129

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.493

High

185138

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

185153

PECA1
Platelet endothelial cell adhesion molecule

1

0

High-throughput

0.493

High

185156

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.493

High

185157

RAB5A
Ras-related protein Rab-5A

1

0

High-throughput

0.493

High

185163

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.493

High

185175

SUOX
Sulfite oxidase, mitochondrial

1

0

High-throughput

0.493

High

185177

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

185179

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

185198

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.493

High

185206

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

185222

CCHCR
Coiled-coil alpha-helical rod protein 1

1

0

High-throughput

0.493

High

185230

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.493

High

182411

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.489

High

185133

SPB7
Serpin B7

1

2

High-throughput

0.489

High

185159

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.489

High

185184

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

185209

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

1

High-throughput

0.489

High

185210

SPA12
Serpin A12

1

2

High-throughput

0.489

High

169326

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

High-throughput

0.481

High

185132

TAD2A
Transcriptional adapter 2-alpha

1

2

High-throughput

0.481

High

185173

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

185225

XPF
DNA repair endonuclease XPF

1

2

Small-scale

0.481

High

185136

ABL1
Tyrosine-protein kinase ABL1

1

0

High-throughput

0.480

High

172272

XPO1
Exportin-1

1

1

High-throughput

0.479

High

185137

SPTA1
Spectrin alpha chain, erythrocytic 1

1

1

Small-scale

0.479

High

185168

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

185145

CP3A4
Cytochrome P450 3A4

1

1

High-throughput

0.470

High

185158

PSB1
Proteasome subunit beta type-1

1

0

Small-scale

0.460

High

185148

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

185162

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

Small-scale

0.458

High

185167

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

185169

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

185171

NOTC1
Neurogenic locus notch homolog protein 1

1

0

Small-scale

0.458

High

185176

BLM
RecQ-like DNA helicase BLM

1

0

Small-scale

0.458

High

185181

SUH
Recombining binding protein suppressor of hairless

1

0

Small-scale

0.458

High

185187

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

0

Small-scale

0.458

High

185192

TOP3A
DNA topoisomerase 3-alpha

1

0

Small-scale

0.458

High

185203

ABRX1
BRCA1-A complex subunit Abraxas 1

1

0

Small-scale

0.458

High

185205

DPOLN
DNA polymerase nu

1

0

Small-scale

0.458

High

185233

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

185237

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

0

Small-scale

0.458

High

185252

FAN1
Fanconi-associated nuclease 1

1

0

Small-scale

0.458

High

185155

K1C15
Keratin, type I cytoskeletal 15

1

1

High-throughput

0.457

High

185151

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.438

High

185189

CENPR
Centromere protein R

1

0

High-throughput

0.438

High

185240

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.438

High

185241

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.438

High

185248

XPO7
Exportin-7

1

1

High-throughput

0.437

High

185197

FSCN1
Fascin

1

0

Small-scale

0.426

High

185200

VASN
Vasorin

1

0

High-throughput

0.426

High

185243

S39A9
Zinc transporter ZIP9

1

0

High-throughput

0.426

High

185140

GLPB
Glycophorin-B

2

0

High-throughput

0.328

High

185166

CD70
CD70 antigen

2

0

High-throughput

0.328

High

185219

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

0

High-throughput

0.316

High

185183

TLE5
TLE family member 5

1

0

High-throughput

0.292

High

185185

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.292

High

185207

NECA2
N-terminal EF-hand calcium-binding protein 2

1

0

High-throughput

0.292

High

185212

IHO1
Interactor of HORMAD1 protein 1

1

0

High-throughput

0.292

High

185215

LNX2
Ligand of Numb protein X 2

1

0

High-throughput

0.292

High

185220

CBY2
Protein chibby homolog 2

1

0

High-throughput

0.292

High

185253

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.292

High

185216

SAMD3
Sterile alpha motif domain-containing protein 3

1

0

High-throughput

0.282

High

185130

CATL2
Cathepsin L2

1

0

High-throughput

0.279

Low

185161

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.279

Low

185178

LOXL3
Lysyl oxidase homolog 3

1

0

High-throughput

0.279

Low

185195

DSC3
Desmocollin-3

1

0

High-throughput

0.279

Low

185196

CDSN
Corneodesmosin

1

0

High-throughput

0.279

Low

185199

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

185226

ZHX1R
Zinc fingers and homeoboxes protein 1, isoform 2

1

0

High-throughput

0.279

Low

185227

VPS50
Syndetin

1

0

High-throughput

0.279

Low

185254

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

109345

G5E9A7
DM1 locus, WD repeat containing

1

0

High-throughput

0.268

Low

185134

WFS1
Wolframin

1

0

High-throughput

0.268

Low

185191

PLD1
Phospholipase D1

1

0

High-throughput

0.268

Low

185208

ZN329
Zinc finger protein 329

1

0

High-throughput

0.268

Low

185223

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

185224

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.268

Low

185232

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

185245

NLGN3
Neuroligin-3

1

0

Small-scale

0.265

Low

185131

RTN2
Reticulon-2

1

0

Small-scale

0.251

Low

185250

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.251

Low

185239

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025