Protein: S1PR5
Sphingosine 1-phosphate receptor 5 (S1P receptor 5) (S1P5) (Endothelial differentiation G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor Edg-8) (S1P receptor Edg-8)

Gene: S1PR5
Organism: Homo sapiens
Interactions: 14
UniProt ID: Q9H228

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0019222 - regulation of metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1406358

GPR21
Probable G-protein coupled receptor 21

2

19

High-throughput

0.811

High

835498

CCR2
C-C chemokine receptor type 2

1

16

High-throughput

0.698

High

1242932

S39A4
Zinc transporter ZIP4

3

20

High-throughput

0.667

High

870786

CXA8
Gap junction alpha-8 protein

2

10

High-throughput

0.606

High

338709

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.602

High

132659

UPK1A
Uroplakin-1a

1

20

High-throughput

0.536

High

688681

NKG2C
NKG2-C type II integral membrane protein

1

12

High-throughput

0.536

High

771815

SCN4A
Sodium channel protein type 4 subunit alpha

1

5

High-throughput

0.536

High

1431454

TTYH1
Protein tweety homolog 1

1

14

High-throughput

0.536

High

1407657

SMO
Protein smoothened

1

0

High-throughput

0.518

High

1431455

P63
Tumor protein 63

1

0

Small-scale

0.513

High

1294761

LYPD6
Ly6/PLAUR domain-containing protein 6

1

0

High-throughput

0.458

High

1359315

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

1431456

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025