Protein: LYPD6
Ly6/PLAUR domain-containing protein 6

Gene: LYPD6
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q86Y78

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0030425 - dendrite
GO:0030550 - acetylcholine receptor inhibitor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

175393

PLXB2
Plexin-B2

3

1

High-throughput

0.667

High

896815

DYN2
Dynamin-2

3

2

High-throughput

0.667

High

1050697

DYN1
Dynamin-1

3

2

High-throughput

0.667

High

1294753

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

3

1

High-throughput

0.667

High

1294763

TMX1
Thioredoxin-related transmembrane protein 1

3

1

High-throughput

0.667

High

1294764

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

3

1

High-throughput

0.667

High

1294769

DYN3
Dynamin-3

3

2

High-throughput

0.667

High

1125858

FZD2
Frizzled-2

3

0

High-throughput

0.638

High

1294750

SIDT2
SID1 transmembrane family member 2

3

0

High-throughput

0.638

High

1294755

S47A1
Multidrug and toxin extrusion protein 1

3

0

High-throughput

0.638

High

1294767

MINP1
Multiple inositol polyphosphate phosphatase 1

3

0

High-throughput

0.638

High

1294768

S12A4
Solute carrier family 12 member 4

3

0

High-throughput

0.638

High

1058506

CKAP4
Cytoskeleton-associated protein 4

2

0

High-throughput

0.585

High

1294752

LMBR1
Limb region 1 protein homolog

2

0

High-throughput

0.585

High

1294754

GCP3
Gamma-tubulin complex component 3

2

0

High-throughput

0.585

High

1294765

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

1

High-throughput

0.479

High

565657

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.458

High

611213

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

1105216

S39A6
Zinc transporter ZIP6

1

0

High-throughput

0.458

High

1294751

ZNT7
Zinc transporter 7

1

0

High-throughput

0.458

High

1294756

TECT2
Tectonic-2

1

0

High-throughput

0.458

High

1294761

S1PR5
Sphingosine 1-phosphate receptor 5

1

0

High-throughput

0.458

High

607949

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

6

Small-scale

0.445

High

720420

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

6

Small-scale

0.445

High

723241

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

6

Small-scale

0.445

High

733705

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

6

Small-scale

0.445

High

784830

ACHA7
Neuronal acetylcholine receptor subunit alpha-7

1

6

Small-scale

0.445

High

851162

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

6

Small-scale

0.445

High

1154312

ACHA6
Neuronal acetylcholine receptor subunit alpha-6

1

6

Small-scale

0.445

High

1248620

LCLT1
Lysocardiolipin acyltransferase 1

1

1

High-throughput

0.437

High

773918

SOAT1
Sterol O-acyltransferase 1

3

0

High-throughput

0.347

High

1238646

TM214
Transmembrane protein 214

3

0

High-throughput

0.347

High

1294757

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

3

0

High-throughput

0.347

High

1294760

METL9
Protein-L-histidine N-pros-methyltransferase

3

0

High-throughput

0.347

High

1294762

TM245
Transmembrane protein 245

3

0

High-throughput

0.347

High

1294759

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.318

High

1294766

S18L2
SS18-like protein 2

2

0

High-throughput

0.316

High

1294758

LMF1
Lipase maturation factor 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025