Protein: UPK1A
Uroplakin-1a (UP1a) (Tetraspanin-21) (Tspan-21) (Uroplakin Ia) (UPIa) (UPKa)

Gene: UPK1A
Organism: Homo sapiens
Interactions: 150
UniProt ID: O00322

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0016020 - membrane
GO:0030855 - epithelial cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

132648

S29A1
Equilibrative nucleoside transporter 1

2

2

High-throughput

0.628

High

132664

ALG9
Alpha-1,2-mannosyltransferase ALG9

2

1

High-throughput

0.628

High

132536

UPK2
Uroplakin-2

1

1

Small-scale

0.618

High

132538

RER1
Protein RER1

1

2

High-throughput

0.536

High

132539

PEPL
Periplakin

1

9

High-throughput

0.536

High

132540

FZD7
Frizzled-7

1

9

High-throughput

0.536

High

132541

HIP1R
Huntingtin-interacting protein 1-related protein

1

8

High-throughput

0.536

High

132543

PRAF3
PRA1 family protein 3

1

5

High-throughput

0.536

High

132544

AGRL1
Adhesion G protein-coupled receptor L1

1

17

High-throughput

0.536

High

132545

ECEL1
Endothelin-converting enzyme-like 1

1

9

High-throughput

0.536

High

132547

AACT
Alpha-1-antichymotrypsin

1

8

High-throughput

0.536

High

132551

APOD
Apolipoprotein D

1

3

High-throughput

0.536

High

132552

S10A8
Protein S100-A8

1

7

High-throughput

0.536

High

132553

S10A9
Protein S100-A9

1

11

High-throughput

0.536

High

132554

INVO
Involucrin

1

5

High-throughput

0.536

High

132555

HMOX1
Heme oxygenase 1

1

2

High-throughput

0.536

High

132557

GP1BB
Platelet glycoprotein Ib beta chain

1

7

High-throughput

0.536

High

132558

ANXA8
Annexin A8

1

5

High-throughput

0.536

High

132560

PLAK
Junction plakoglobin

1

2

High-throughput

0.536

High

132562

CBR1
Carbonyl reductase [NADPH] 1

1

7

High-throughput

0.536

High

132563

CXA1
Gap junction alpha-1 protein

1

10

High-throughput

0.536

High

132565

RAB5A
Ras-related protein Rab-5A

1

1

High-throughput

0.536

High

132566

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

132567

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

15

High-throughput

0.536

High

132571

SPB3
Serpin B3

1

6

High-throughput

0.536

High

132572

S10A7
Protein S100-A7

1

11

High-throughput

0.536

High

132574

SOAT1
Sterol O-acyltransferase 1

1

3

High-throughput

0.536

High

132575

CXG1
Gap junction gamma-1 protein

1

10

High-throughput

0.536

High

132577

LEG7
Galectin-7

1

11

High-throughput

0.536

High

132578

SC6A9
Sodium- and chloride-dependent glycine transporter 1

1

1

High-throughput

0.536

High

132579

SPB4
Serpin B4

1

6

High-throughput

0.536

High

132580

AGRE5
Adhesion G protein-coupled receptor E5

1

16

High-throughput

0.536

High

132582

CTR2
Cationic amino acid transporter 2

1

9

High-throughput

0.536

High

132583

AT12A
Potassium-transporting ATPase alpha chain 2

1

10

High-throughput

0.536

High

132584

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.536

High

132585

RAB5B
Ras-related protein Rab-5B

1

1

High-throughput

0.536

High

132588

NGAL
Neutrophil gelatinase-associated lipocalin

1

3

High-throughput

0.536

High

132589

CKAP4
Cytoskeleton-associated protein 4

1

9

High-throughput

0.536

High

132590

RHG01
Rho GTPase-activating protein 1

1

3

High-throughput

0.536

High

132592

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

1

2

High-throughput

0.536

High

132593

FZD2
Frizzled-2

1

9

High-throughput

0.536

High

132595

CYTM
Cystatin-M

1

1

High-throughput

0.536

High

132598

D19L1
Protein C-mannosyl-transferase DPY19L1

1

3

High-throughput

0.536

High

132599

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

5

High-throughput

0.536

High

132601

ANO6
Anoctamin-6

1

1

High-throughput

0.536

High

132602

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

1

High-throughput

0.536

High

132603

TM164
Transmembrane protein 164

1

1

High-throughput

0.536

High

132606

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.536

High

132608

MFS12
Major facilitator superfamily domain-containing protein 12

1

1

High-throughput

0.536

High

132609

MBOA5
Lysophospholipid acyltransferase 5

1

5

High-throughput

0.536

High

132612

CERS6
Ceramide synthase 6

1

5

High-throughput

0.536

High

132616

GDPD3
Lysophospholipase D GDPD3

1

2

High-throughput

0.536

High

132617

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

8

High-throughput

0.536

High

132620

NLRX1
NLR family member X1

1

2

High-throughput

0.536

High

132621

TM219
Insulin-like growth factor-binding protein 3 receptor

1

1

High-throughput

0.536

High

132622

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

4

High-throughput

0.536

High

132623

S15A4
Solute carrier family 15 member 4

1

3

High-throughput

0.536

High

132625

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.536

High

132626

AT11C
Phospholipid-transporting ATPase IG

1

8

High-throughput

0.536

High

132628

TM87A
Transmembrane protein 87A

1

5

High-throughput

0.536

High

132629

LEMD2
LEM domain-containing protein 2

1

3

High-throughput

0.536

High

132630

CTL5
Choline transporter-like protein 5

1

8

High-throughput

0.536

High

132632

SPP2B
Signal peptide peptidase-like 2B

1

2

High-throughput

0.536

High

132634

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

1

3

High-throughput

0.536

High

132635

MOT10
Monocarboxylate transporter 10

1

7

High-throughput

0.536

High

132636

NAT14
Probable N-acetyltransferase 14

1

2

High-throughput

0.536

High

132637

CTL1
Choline transporter-like protein 1

1

8

High-throughput

0.536

High

132638

EVPL
Envoplakin

1

10

High-throughput

0.536

High

132640

S47A1
Multidrug and toxin extrusion protein 1

1

1

High-throughput

0.536

High

132642

CPNS2
Calpain small subunit 2

1

3

High-throughput

0.536

High

132643

TLCD4
TLC domain-containing protein 4

1

1

High-throughput

0.536

High

132644

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

5

High-throughput

0.536

High

132645

GSDMA
Gasdermin-A

1

1

High-throughput

0.536

High

132646

DIRC2
Solute carrier family 49 member 4

1

1

High-throughput

0.536

High

132647

ABCA3
Phospholipid-transporting ATPase ABCA3

1

2

High-throughput

0.536

High

132649

CIB1
Calcium and integrin-binding protein 1

1

2

High-throughput

0.536

High

132651

NDC1
Nucleoporin NDC1

1

2

High-throughput

0.536

High

132654

TACAN
Transmembrane protein 120A

1

4

High-throughput

0.536

High

132655

S12A9
Solute carrier family 12 member 9

1

13

High-throughput

0.536

High

132657

TM222
Transmembrane protein 222

1

2

High-throughput

0.536

High

132658

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.536

High

132659

S1PR5
Sphingosine 1-phosphate receptor 5

1

20

High-throughput

0.536

High

132662

FZD8
Frizzled-8

1

9

High-throughput

0.536

High

132666

FZD3
Frizzled-3

1

9

High-throughput

0.536

High

132668

ZDH18
Palmitoyltransferase ZDHHC18

1

10

High-throughput

0.536

High

132673

B4GT7
Beta-1,4-galactosyltransferase 7

1

1

High-throughput

0.536

High

132675

PCYOX
Prenylcysteine oxidase 1

1

1

High-throughput

0.536

High

132677

POMT2
Protein O-mannosyl-transferase 2

1

2

High-throughput

0.536

High

132678

FZD1
Frizzled-1

1

9

High-throughput

0.536

High

132679

POMT1
Protein O-mannosyl-transferase 1

1

2

High-throughput

0.536

High

132680

MTCH2
Mitochondrial carrier homolog 2

1

3

High-throughput

0.536

High

126211

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.513

High

132546

AL1A1
Aldehyde dehydrogenase 1A1

1

0

High-throughput

0.513

High

132561

ARSA
Arylsulfatase A

1

0

High-throughput

0.513

High

132569

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.513

High

132586

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.513

High

132591

TMM62
Transmembrane protein 62

1

0

High-throughput

0.513

High

132594

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

132596

H2A2C
Histone H2A type 2-C

1

0

High-throughput

0.513

High

132597

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.513

High

132605

P20D1
N-fatty-acyl-amino acid synthase/hydrolase PM20D1

1

0

High-throughput

0.513

High

132607

TM214
Transmembrane protein 214

1

0

High-throughput

0.513

High

132611

SBSN
Suprabasin

1

0

High-throughput

0.513

High

132613

TMPPE
Transmembrane protein with metallophosphoesterase domain

1

0

High-throughput

0.513

High

132614

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

132615

PGAP1
GPI inositol-deacylase

1

0

High-throughput

0.513

High

132619

T179B
Transmembrane protein 179B

1

0

High-throughput

0.513

High

132627

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

132633

TRPM4
Transient receptor potential cation channel subfamily M member 4

1

0

High-throughput

0.513

High

132652

LMF2
Lipase maturation factor 2

1

0

High-throughput

0.513

High

132656

ADT4
ADP/ATP translocase 4

1

0

High-throughput

0.513

High

132665

S52A2
Solute carrier family 52, riboflavin transporter, member 2

1

0

High-throughput

0.513

High

132671

CC167
Coiled-coil domain-containing protein 167

1

0

High-throughput

0.513

High

132672

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.513

High

132676

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.513

High

49414

TM223
Transmembrane protein 223

1

1

High-throughput

0.489

High

132537

IMPA2
Inositol monophosphatase 2

1

1

High-throughput

0.489

High

132542

CBR3
Carbonyl reductase [NADPH] 3

1

7

High-throughput

0.489

High

132568

AOFB
Amine oxidase [flavin-containing] B

1

2

High-throughput

0.489

High

132570

S10A2
Protein S100-A2

1

11

High-throughput

0.489

High

132576

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

1

High-throughput

0.489

High

132581

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.489

High

132587

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

1

High-throughput

0.489

High

132600

SMTL2
Smoothelin-like protein 2

1

5

High-throughput

0.489

High

132610

LTMD1
LETM1 domain-containing protein 1

1

2

High-throughput

0.489

High

132618

D19L4
Probable C-mannosyltransferase DPY19L4

1

3

High-throughput

0.489

High

132624

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

5

High-throughput

0.489

High

132631

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

4

High-throughput

0.489

High

132641

BSCL2
Seipin

1

3

High-throughput

0.489

High

132653

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

1

High-throughput

0.489

High

132660

GAN
Gigaxonin

1

3

High-throughput

0.489

High

132667

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

2

High-throughput

0.489

High

132669

TM39A
Transmembrane protein 39A

1

1

High-throughput

0.489

High

132670

CALL5
Calmodulin-like protein 5

1

2

High-throughput

0.489

High

132573

SFTPD
Pulmonary surfactant-associated protein D

1

7

Small-scale

0.481

High

69451

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.445

High

132548

IGKC
Immunoglobulin kappa constant

1

7

High-throughput

0.445

High

132549

IGHG1
Immunoglobulin heavy constant gamma 1

1

10

High-throughput

0.445

High

132550

IGHG2
Immunoglobulin heavy constant gamma 2

1

12

High-throughput

0.445

High

75631

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

132556

GPHRB
Golgi pH regulator B

1

6

High-throughput

0.437

High

85326

GPHRA
Golgi pH regulator A

1

6

High-throughput

0.407

High

132559

CX7A2
Cytochrome c oxidase subunit 7A2, mitochondrial

1

0

High-throughput

0.279

Low

132564

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

132604

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.279

Low

132639

ISOC2
Isochorismatase domain-containing protein 2

1

0

High-throughput

0.279

Low

132650

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.279

Low

132661

PIGM
GPI alpha-1,4-mannosyltransferase I, catalytic subunit

1

0

High-throughput

0.279

Low

132663

TM231
Transmembrane protein 231

1

0

High-throughput

0.279

Low

132674

NPS3A
Protein NipSnap homolog 3A

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025