Protein: FSP1
Ferroptosis suppressor protein 1 (FSP1) (EC 1.6.5.-) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (AMID) (p53-responsive gene 3 protein)

Gene: FSP1, AIFM2
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q9BRQ8

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0004174 - electron-transferring-flavoprotein dehydrogenase activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1292740

TRI69
E3 ubiquitin-protein ligase TRIM69

3

2

Small-scale

0.653

High

1411618

TRI54
Tripartite motif-containing protein 54

3

8

Small-scale

0.653

High

623508

RO52
E3 ubiquitin-protein ligase TRIM21

1

2

Small-scale

0.561

High

251473

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

1

2

High-throughput

0.536

High

994349

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

3

High-throughput

0.536

High

1229855

CYTSA
Cytospin-A

1

4

High-throughput

0.536

High

1295445

C2CD5
C2 domain-containing protein 5

1

1

High-throughput

0.536

High

1411620

ECHD1
Ethylmalonyl-CoA decarboxylase

1

4

High-throughput

0.536

High

1033420

CDR2
Cerebellar degeneration-related protein 2

1

0

High-throughput

0.513

High

1226726

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

0

High-throughput

0.513

High

1411617

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.513

High

1291739

SESD1
SEC14 domain and spectrin repeat-containing protein 1

1

4

High-throughput

0.489

High

137797

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.479

High

242742

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

414517

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

605798

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

High-throughput

0.479

High

1100306

TIF1B
Transcription intermediary factor 1-beta

1

4

Small-scale

0.479

High

1255282

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1333974

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

1411622

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

377706

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

1380641

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1411619

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

372998

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.445

High

538851

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

3

High-throughput

0.445

High

844861

EAA1
Excitatory amino acid transporter 1

1

0

High-throughput

0.426

High

1389573

SAAL1
Protein SAAL1

1

0

High-throughput

0.426

High

1278561

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

1

High-throughput

0.407

High

1322740

CNPY4
Protein canopy homolog 4

2

0

High-throughput

0.316

High

1332365

IQUB
IQ motif and ubiquitin-like domain-containing protein

1

0

High-throughput

0.279

Low

1411621

USE1
Vesicle transport protein USE1

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025