Protein: LYAM2
E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E)

Gene: LYAM2, SELE
Organism: Homo sapiens
Interactions: 34
UniProt ID: P16581

Gene Ontology (top 5):
GO:0002092 - positive regulation of receptor internalization
GO:0002523 - leukocyte migration involved in inflammatory response
GO:0002687 - positive regulation of leukocyte migration
GO:0004888 - transmembrane signaling receptor activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

570755

LYAM1
L-selectin

1

12

Small-scale

0.665

High

597867

ACTA
Actin, aortic smooth muscle

1

1

Small-scale

0.647

High

597871

LG3BP
Galectin-3-binding protein

1

3

Small-scale

0.647

High

331706

MTMR5
Myotubularin-related protein 5

2

1

High-throughput

0.628

High

597872

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

2

1

High-throughput

0.628

High

597873

DIP2A
Disco-interacting protein 2 homolog A

2

1

High-throughput

0.628

High

445629

CEAM5
Cell adhesion molecule CEACAM5

1

1

Small-scale

0.618

High

597862

MUC18
Cell surface glycoprotein MUC18

1

2

Small-scale

0.618

High

597875

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

2

0

High-throughput

0.602

High

597858

NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

3

Small-scale

0.584

High

597879

DIP2B
Disco-interacting protein 2 homolog B

2

1

High-throughput

0.574

High

597869

FAK1
Focal adhesion kinase 1

1

6

Small-scale

0.561

High

597856

VINC
Vinculin

1

0

Small-scale

0.537

High

597865

PAXI
Paxillin

1

0

Small-scale

0.537

High

425214

IC1
Plasma protease C1 inhibitor

1

3

Small-scale

0.515

High

597857

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

Small-scale

0.515

High

597876

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

597870

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

6

Small-scale

0.506

High

597859

FLNA
Filamin-A

1

3

Small-scale

0.501

High

597877

GSLG1
Golgi apparatus protein 1

1

1

Small-scale

0.501

High

597878

TRI54
Tripartite motif-containing protein 54

1

2

High-throughput

0.494

High

597866

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

597861

SYUA
Alpha-synuclein

1

1

High-throughput

0.481

High

141901

PODXL
Podocalyxin

1

4

Small-scale

0.479

High

591211

CD44
CD44 antigen

1

11

Small-scale

0.479

High

597864

MK09
Mitogen-activated protein kinase 9

1

2

Small-scale

0.479

High

597868

TF65
Transcription factor p65

1

3

Small-scale

0.479

High

429254

JUN
Transcription factor Jun

1

5

Small-scale

0.437

High

583432

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

4

Small-scale

0.437

High

597863

MK08
Mitogen-activated protein kinase 8

1

2

Small-scale

0.437

High

597874

MK14
Mitogen-activated protein kinase 14

1

2

Small-scale

0.437

High

301330

WFS1
Wolframin

1

0

High-throughput

0.268

Low

162458

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.249

Low

597860

HXA9
Homeobox protein Hox-A9

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025