Protein: COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (EC 2.1.1.201) (2-hexaprenyl-6-methoxy-1,4-benzoquinol methyltransferase) (Ubiquinone biosynthesis methyltransferase COQ5)

Gene: COQ5
Organism: Saccharomyces cerevisiae S288C
Interactions: 33
UniProt ID: P49017

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005759 - mitochondrial matrix
GO:0006744 - ubiquinone biosynthetic process
GO:0008425 - 2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

878370

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

3

2

Small-scale

0.656

High

878363

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

2

3

Small-scale

0.584

High

878361

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

9

Small-scale

0.575

High

524501

HSP71
Heat shock protein SSA1

2

3

High-throughput

0.533

High

878372

TAR1
Protein TAR1

1

0

Small-scale

0.504

High

819212

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.504

High

778827

PMIP
Mitochondrial intermediate peptidase

1

0

Small-scale

0.480

High

150073

COQ4
Ubiquinone biosynthesis protein COQ4, mitochondrial

1

2

High-throughput

0.479

High

594973

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

3

High-throughput

0.479

High

694477

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

4

Small-scale

0.479

High

835596

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

2

High-throughput

0.479

High

557019

AAKG
5'-AMP-activated protein kinase subunit gamma

1

1

High-throughput

0.464

High

456429

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

510640

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

673514

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

685106

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

0

High-throughput

0.458

High

737474

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

878362

SHY1
Cytochrome oxidase assembly protein SHY1

1

0

Small-scale

0.458

High

878371

COQ11
MIOREX complex component 2

1

0

Small-scale

0.458

High

878367

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

545497

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.407

High

676150

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.407

High

741939

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.407

High

805354

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

0

High-throughput

0.265

Low

878364

YIF1
Protein transport protein YIF1

1

0

High-throughput

0.265

Low

878366

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.265

Low

878369

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.265

Low

656812

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.261

Low

739691

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

792137

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.249

Low

878368

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

878365

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025