Protein: COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial (3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase) (3-demethylubiquinol 3-O-methyltransferase) (EC 2.1.1.64) (3-demethylubiquinone 3-O-methyltransferase) (EC 2.1.1.-) (3-demethylubiquinone-6 3-O-methyltransferase) (Hexaprenyldihydroxybenzoate methyltransferase) (Polyprenyldihydroxybenzoate methyltransferase) (EC 2.1.1.114)

Gene: COQ3
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: P27680

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006744 - ubiquinone biosynthetic process
GO:0010420 - polyprenyldihydroxybenzoate methyltransferase activity
GO:0031314 - extrinsic component of mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

150064

COQ4
Ubiquinone biosynthesis protein COQ4, mitochondrial

2

1

Small-scale

0.584

High

510255

HSP77
Import motor subunit, mitochondrial

2

1

High-throughput

0.584

High

694473

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

2

1

Small-scale

0.584

High

694485

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

1

Small-scale

0.584

High

694486

COQ11
MIOREX complex component 2

2

0

Small-scale

0.559

High

523237

HSP71
Heat shock protein SSA1

2

3

Small-scale

0.533

High

368139

THDH
Threonine dehydratase, mitochondrial

1

1

High-throughput

0.479

High

484732

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

526076

HSP72
Heat shock protein SSA2

1

3

Small-scale

0.479

High

549935

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

Small-scale

0.479

High

594895

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

622328

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

626626

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.479

High

635938

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

673474

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

1

High-throughput

0.479

High

694461

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

1

High-throughput

0.479

High

694462

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

1

High-throughput

0.479

High

694466

PREP
Presequence protease, mitochondrial

1

2

High-throughput

0.479

High

694471

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

1

High-throughput

0.479

High

694475

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

694477

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

4

Small-scale

0.479

High

694479

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

3

Small-scale

0.479

High

366958

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.458

High

417043

VDAC1
Non-selective voltage-gated ion channel 1

1

0

Small-scale

0.458

High

452636

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

456353

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.458

High

604915

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

642123

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

654585

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

685096

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

0

High-throughput

0.458

High

694464

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.458

High

694465

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

694468

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.458

High

694469

RT21
Small ribosomal subunit protein bS21m

1

0

Small-scale

0.458

High

694470

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

694474

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

694480

ATPJ
ATP synthase subunit e, mitochondrial

1

0

Small-scale

0.458

High

694483

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

481514

HSP73
Heat shock protein SSA3

1

3

Small-scale

0.437

High

645694

HSP74
Heat shock protein SSA4

1

3

Small-scale

0.437

High

694463

BMH1
Protein BMH1

1

2

Small-scale

0.437

High

694467

BMH2
Protein BMH2

1

2

Small-scale

0.437

High

694482

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

694472

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

64221

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

380995

H2B1
Histone H2B.1

1

0

Small-scale

0.249

Low

531632

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

694476

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.249

Low

694478

PEF1
Peflin

1

0

Small-scale

0.249

Low

694481

HPC2
Histone promoter control protein 2

1

0

Small-scale

0.249

Low

694484

SAS4
Something about silencing protein 4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025