Protein: SPHK2
Sphingosine kinase 2 (SK 2) (SPK 2) (EC 2.7.1.91)

Gene: SPHK2
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q9NRA0

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0001568 - blood vessel development
GO:0001727 - lipid kinase activity
GO:0002720 - positive regulation of cytokine production involved in immune response
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1104267

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

3

Small-scale

0.552

High

522141

BCL2
Apoptosis regulator Bcl-2

1

0

Small-scale

0.537

High

902096

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.536

High

1386595

OPTN
Optineurin

1

5

High-throughput

0.515

High

960909

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

1336101

C2C4A
C2 calcium-dependent domain-containing protein 4A

1

0

High-throughput

0.513

High

1448093

NGN3
Neurogenin-3

1

0

High-throughput

0.513

High

440747

FYN
Tyrosine-protein kinase Fyn

1

3

Small-scale

0.501

High

463789

LYN
Tyrosine-protein kinase Lyn

1

3

Small-scale

0.501

High

986752

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.480

High

156671

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

Small-scale

0.479

High

998847

H31
Histone H3.1

1

1

Small-scale

0.479

High

1045812

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1123143

FHL2
Four and a half LIM domains protein 2

1

3

Small-scale

0.479

High

1123835

DCTN1
Dynactin subunit 1

1

2

Small-scale

0.479

High

1400029

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

3

Small-scale

0.479

High

1448091

HECW2
E3 ubiquitin-protein ligase HECW2

1

3

High-throughput

0.479

High

1448092

XPO7
Exportin-7

1

1

High-throughput

0.479

High

1448094

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

Small-scale

0.458

High

1414902

THUM3
tRNA

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025