Protein: UFC1
Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1)

Gene: UFC1
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q9Y3C8

Gene Ontology (top 5):
GO:0007420 - brain development
GO:0032649 - regulation of type II interferon production
GO:0034976 - response to endoplasmic reticulum stress
GO:0061657 - UFM1 conjugating enzyme activity
GO:0061709 - reticulophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1393859

DDRGK
DDRGK domain-containing protein 1

6

0

Small-scale

0.890

High

320175

UFL1
E3 UFM1-protein ligase 1

4

0

Small-scale

0.864

High

964558

UFM1
Ubiquitin-fold modifier 1

2

0

Small-scale

0.748

High

1429217

UBA5
Ubiquitin-like modifier-activating enzyme 5

6

1

Small-scale

0.736

High

1394820

CK5P3
CDK5 regulatory subunit-associated protein 3

4

0

Small-scale

0.667

High

944599

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.580

High

243365

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.493

High

1491187

X5D778
Ankyrin repeat domain 11 isoform A

1

1

High-throughput

0.470

High

567528

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

961585

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.458

High

1280625

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1248001

ANR11
Ankyrin repeat domain-containing protein 11

1

1

High-throughput

0.439

High

1392963

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

1459089

FXL17
F-box/LRR-repeat protein 17

1

0

Small-scale

0.288

High

733475

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

1491186

SAR1B
Small COPII coat GTPase SAR1B

1

0

High-throughput

0.279

Low

1317068

KIRR3
Kin of IRRE-like protein 3

1

0

Small-scale

0.264

Low

170448

AURKA
Aurora kinase A

1

0

High-throughput

0.249

Low

590101

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696940

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769585

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

822920

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.249

Low

1135483

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

0

High-throughput

0.249

Low

1135868

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1256215

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1398325

CFA44
Cilia- and flagella-associated protein 44

1

0

High-throughput

0.249

Low

1428940

PIP30
PSME3-interacting protein

1

0

High-throughput

0.249

Low

261332

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025