Protein: KLHL3
Kelch-like protein 3

Gene: KLHL3
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q9UH77

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005198 - structural molecule activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042768

CUL3
Cullin-3

18

20

Small-scale

0.987

High

1049352

KEAP1
Kelch-like ECH-associated protein 1

4

20

High-throughput

0.895

High

1120826

KLH12
Kelch-like protein 12

4

19

High-throughput

0.895

High

307227

KLHL2
Kelch-like protein 2

4

18

High-throughput

0.894

High

1355221

KLHL3
Kelch-like protein 3

2

17

Small-scale

0.757

High

1294943

WNK4
Serine/threonine-protein kinase WNK4

10

8

Small-scale

0.757

High

1330745

WNK1
Serine/threonine-protein kinase WNK1

6

12

Small-scale

0.730

High

1164602

KLH17
Kelch-like protein 17

1

18

High-throughput

0.691

High

1354637

FXL17
F-box/LRR-repeat protein 17

1

14

High-throughput

0.691

High

1317206

WNK3
Serine/threonine-protein kinase WNK3

4

8

Small-scale

0.686

High

1121506

KLH26
Kelch-like protein 26

1

20

High-throughput

0.618

High

1043281

CUL4A
Cullin-4A

1

20

High-throughput

0.618

High

921464

RBX1
E3 ubiquitin-protein ligase RBX1

2

7

Small-scale

0.595

High

1355222

WNK2
Serine/threonine-protein kinase WNK2

2

13

Small-scale

0.584

High

155657

TNPO2
Transportin-2

2

2

High-throughput

0.553

High

166795

CE290
Centrosomal protein of 290 kDa

1

5

High-throughput

0.536

High

915528

ACTA
Actin, aortic smooth muscle

1

7

High-throughput

0.536

High

158053

KLF11
Krueppel-like factor 11

1

2

High-throughput

0.515

High

258237

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.515

High

349705

RASH
GTPase HRas

1

1

High-throughput

0.515

High

414100

GELS
Gelsolin

1

1

High-throughput

0.515

High

877160

CASP6
Caspase-6

1

3

High-throughput

0.515

High

89993

D6R9G5
Kelch like family member 2

1

20

High-throughput

0.514

High

568818

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

3

Small-scale

0.501

High

682058

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

Small-scale

0.501

High

895941

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

5

Small-scale

0.501

High

994120

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

1

Small-scale

0.501

High

49993

PXDNL
Probable oxidoreductase PXDNL

1

1

High-throughput

0.489

High

313634

TNF6B
Tumor necrosis factor receptor superfamily member 6B

1

2

High-throughput

0.489

High

316194

CBX6
Chromobox protein homolog 6

1

3

High-throughput

0.489

High

1217455

NUDC3
NudC domain-containing protein 3

1

20

High-throughput

0.489

High

377784

GCR
Glucocorticoid receptor

1

3

High-throughput

0.479

High

909282

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

1036980

SQSTM
Sequestosome-1

1

5

Small-scale

0.479

High

527864

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.470

High

609595

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.470

High

874011

S12A3
Solute carrier family 12 member 3

1

0

Small-scale

0.458

High

881981

CLD8
Claudin-8

1

0

Small-scale

0.458

High

1063058

MO4L2
Mortality factor 4-like protein 2

1

1

High-throughput

0.439

High

1223483

CF206
Cilia- and flagella-associated protein 206

1

1

High-throughput

0.439

High

818844

SOX9
Transcription factor SOX-9

1

6

Small-scale

0.437

High

236526

PSPN
Persephin

1

0

High-throughput

0.279

Low

1133977

RM02
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024