Protein: SMCO4
Single-pass membrane and coiled-coil domain-containing protein 4 (Protein FN5)

Gene: SMCO4
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q9NRQ5

Gene Ontology (top 5):
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

239397

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

4

0

High-throughput

0.673

High

722634

CTR1
High affinity cationic amino acid transporter 1

2

1

High-throughput

0.606

High

1448765

SCN3B
Sodium channel regulatory subunit beta-3

2

1

High-throughput

0.606

High

161367

PTGES
Prostaglandin E synthase

2

0

High-throughput

0.580

High

167007

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.580

High

211952

SPIT1
Kunitz-type protease inhibitor 1

2

0

High-throughput

0.580

High

329668

LERL1
Leptin receptor overlapping transcript-like 1

2

0

High-throughput

0.580

High

633869

MPRD
Cation-dependent mannose-6-phosphate receptor

2

0

High-throughput

0.580

High

668234

CXCR2
C-X-C chemokine receptor type 2

2

0

High-throughput

0.580

High

690398

STOM
Stomatin

2

0

High-throughput

0.580

High

1308350

TM139
Transmembrane protein 139

2

0

High-throughput

0.580

High

1324867

LRC25
Leucine-rich repeat-containing protein 25

2

0

High-throughput

0.580

High

1329396

TEX29
Testis-expressed protein 29

2

0

High-throughput

0.580

High

1349125

F174A
Membrane protein FAM174A

2

0

High-throughput

0.580

High

1384359

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.580

High

1393135

TMM80
Transmembrane protein 80

2

0

High-throughput

0.580

High

1396404

F210B
Protein FAM210B, mitochondrial

2

0

High-throughput

0.580

High

1420033

SMIM3
Small integral membrane protein 3

2

0

High-throughput

0.580

High

1448767

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

194754

FFAR2
Free fatty acid receptor 2

2

1

High-throughput

0.553

High

1348643

S7A14
Solute carrier family 7 member 14

2

1

High-throughput

0.553

High

950415

KR107
Keratin-associated protein 10-7

1

1

High-throughput

0.523

High

193455

GPR42
G-protein coupled receptor 42

1

1

High-throughput

0.470

High

950016

KR103
Keratin-associated protein 10-3

1

1

High-throughput

0.439

High

1323889

SYNE4
Nesprin-4

3

0

High-throughput

0.352

High

142113

PEX12
Peroxisome assembly protein 12

2

0

High-throughput

0.316

High

168940

TFEC
Transcription factor EC

2

0

High-throughput

0.316

High

332803

KCNK5
Potassium channel subfamily K member 5

2

0

High-throughput

0.316

High

549892

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

590348

MUC1
Mucin-1

2

0

High-throughput

0.316

High

748806

ICAM3
Intercellular adhesion molecule 3

2

0

High-throughput

0.316

High

850871

KI3L1
Killer cell immunoglobulin-like receptor 3DL1

2

0

High-throughput

0.316

High

870794

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.316

High

926851

VMAT1
Chromaffin granule amine transporter

2

0

High-throughput

0.316

High

1109056

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1116643

I10R1
Interleukin-10 receptor subunit alpha

2

0

High-throughput

0.316

High

1142949

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

1207629

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1281197

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

1291507

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.316

High

1307735

CLC10
C-type lectin domain family 10 member A

2

0

High-throughput

0.316

High

1308221

PLD3
5'-3' exonuclease PLD3

2

0

High-throughput

0.316

High

1348883

SYNPR
Synaptoporin

2

0

High-throughput

0.316

High

1351710

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

1391357

WBP1
WW domain-binding protein 1

2

0

High-throughput

0.316

High

1392587

S41A3
Solute carrier family 41 member 3

2

0

High-throughput

0.316

High

1393276

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.316

High

1396496

SUSD3
Sushi domain-containing protein 3

2

0

High-throughput

0.316

High

1407322

GPA33
Cell surface A33 antigen

2

0

High-throughput

0.316

High

1435872

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

0

High-throughput

0.316

High

1438325

CLTRN
Collectrin

2

0

High-throughput

0.316

High

1447155

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

1448764

GKN1
Gastrokine-1

2

0

High-throughput

0.316

High

1448766

HHLA2
HERV-H LTR-associating protein 2

2

0

High-throughput

0.316

High

1448768

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

1230276

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.299

High

1329444

KASH5
Protein KASH5

1

0

High-throughput

0.299

High

386273

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

779734

MOT8
Monocarboxylate transporter 8

1

0

High-throughput

0.251

Low

1186051

SOAT
Sodium-dependent organic anion transporter

1

0

High-throughput

0.251

Low

1187572

AR13B
ADP-ribosylation factor-like protein 13B

1

0

High-throughput

0.251

Low

1428512

ELOV4
Very long chain fatty acid elongase 4

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025