Protein: LAG3
Lymphocyte activation gene 3 protein (LAG-3) (CD antigen CD223) [Cleaved into: Secreted lymphocyte activation gene 3 protein (sLAG-3)]

Gene: LAG3
Organism: Homo sapiens
Interactions: 16
UniProt ID: P18627

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0002270 - plasmacytoid dendritic cell activation
GO:0003823 - antigen binding
GO:0004888 - transmembrane signaling receptor activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

616080

FGL1
Fibrinogen-like protein 1

1

3

Small-scale

0.561

High

239716

PCDH7
Protocadherin-7

1

7

High-throughput

0.536

High

616079

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

2

High-throughput

0.536

High

616081

FAT1
Protocadherin Fat 1

1

4

High-throughput

0.536

High

616082

FREM2
FRAS1-related extracellular matrix protein 2

1

4

High-throughput

0.536

High

616084

PCD20
Protocadherin-20

1

5

High-throughput

0.536

High

616085

AGRV1
Adhesion G-protein coupled receptor V1

1

5

High-throughput

0.536

High

616088

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

3

High-throughput

0.536

High

616089

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

4

High-throughput

0.536

High

616078

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

0

High-throughput

0.513

High

616086

SNX18
Sorting nexin-18

1

0

High-throughput

0.513

High

299863

C1QRF
C1q-related factor

1

6

High-throughput

0.489

High

616090

FBX2
F-box only protein 2

1

6

High-throughput

0.489

High

616087

CPAP
Centrosomal P4.1-associated protein

1

3

Small-scale

0.462

High

616091

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

616083

FBX11
F-box only protein 11

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025