Protein: FGL1
Fibrinogen-like protein 1 (HP-041) (Hepassocin) (HPS) (Hepatocyte-derived fibrinogen-related protein 1) (HFREP-1) (Liver fibrinogen-related protein 1) (LFIRE-1)

Gene: FGL1
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q08830

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0005576 - extracellular region
GO:0005577 - fibrinogen complex
GO:0005615 - extracellular space
GO:0007596 - blood coagulation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1052137

COEA1
Collagen alpha-1(XIV) chain

3

10

High-throughput

0.861

High

1065011

PXDN
Peroxidasin homolog

4

3

High-throughput

0.691

High

366543

TPA
Tissue-type plasminogen activator

3

5

High-throughput

0.667

High

1038970

NUCB1
Nucleobindin-1

3

1

High-throughput

0.667

High

1065007

GOLM1
Golgi membrane protein 1

4

0

High-throughput

0.661

High

1064999

FBX38
F-box only protein 38

3

0

High-throughput

0.638

High

906234

SSDH
Succinate-semialdehyde dehydrogenase, mitochondrial

4

3

High-throughput

0.630

High

1065005

PTGR3
Prostaglandin reductase 3

4

1

High-throughput

0.630

High

1065024

UBA5
Ubiquitin-like modifier-activating enzyme 5

4

1

High-throughput

0.630

High

1065025

LSG1
Large subunit GTPase 1 homolog

4

1

High-throughput

0.630

High

1065012

SORL
Sortilin-related receptor

1

4

High-throughput

0.618

High

471588

CO4A2

2

1

High-throughput

0.611

High

135597

DNM1L
Dynamin-1-like protein

3

1

High-throughput

0.609

High

936311

AFAD
Afadin

3

2

High-throughput

0.609

High

945781

EPIPL
Epiplakin

3

1

High-throughput

0.609

High

1064989

TRIP6
Thyroid receptor-interacting protein 6

3

3

High-throughput

0.609

High

1064998

PKHA7
Pleckstrin homology domain-containing family A member 7

3

1

High-throughput

0.609

High

1065010

DDB2
DNA damage-binding protein 2

3

2

High-throughput

0.609

High

1065027

PTN23
Tyrosine-protein phosphatase non-receptor type 23

3

6

High-throughput

0.609

High

1065033

SLTM
SAFB-like transcription modulator

3

1

High-throughput

0.609

High

1065039

TBE
Tubulin epsilon chain

3

4

High-throughput

0.609

High

1065040

TBD
Tubulin delta chain

3

4

High-throughput

0.609

High

1064980

EPS8
Epidermal growth factor receptor kinase substrate 8

2

2

High-throughput

0.574

High

616080

LAG3
Lymphocyte activation gene 3 protein

1

3

Small-scale

0.561

High

1064983

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

1

High-throughput

0.558

High

652307

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.489

High

1065041

PRR12
Proline-rich protein 12

1

1

High-throughput

0.489

High

1065021

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

1

Small-scale

0.481

High

1064979

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

8

High-throughput

0.445

High

1064984

LAMC2
Laminin subunit gamma-2

1

6

High-throughput

0.445

High

1065016

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

2

High-throughput

0.445

High

1065031

IL1AP
Interleukin-1 receptor accessory protein

1

7

High-throughput

0.445

High

1065043

EMIL1
EMILIN-1

1

1

High-throughput

0.445

High

219623

B2L11
Bcl-2-like protein 11

1

3

High-throughput

0.439

High

1047804

TLE1
Transducin-like enhancer protein 1

1

7

High-throughput

0.437

High

1047957

TLE3
Transducin-like enhancer protein 3

1

7

High-throughput

0.437

High

1065035

TFP11
Tuftelin-interacting protein 11

1

2

High-throughput

0.437

High

1065037

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

458683

SAP
Prosaposin

1

0

High-throughput

0.426

High

1065044

TX264
Testis-expressed protein 264

1

0

High-throughput

0.426

High

1040110

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

6

High-throughput

0.407

High

1064991

KLH22
Kelch-like protein 22

1

2

High-throughput

0.407

High

1065017

TRI47
E3 ubiquitin-protein ligase TRIM47

1

3

High-throughput

0.407

High

244817

TYW4
tRNA wybutosine-synthesizing protein 4

4

0

High-throughput

0.360

High

339366

ETHE1
Persulfide dioxygenase ETHE1, mitochondrial

4

0

High-throughput

0.360

High

622800

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

4

0

High-throughput

0.360

High

1064981

PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2

4

0

High-throughput

0.360

High

1064992

SYAM
Alanine--tRNA ligase, mitochondrial

4

0

High-throughput

0.360

High

1064997

AMERL
AMMECR1-like protein

4

0

High-throughput

0.360

High

1065002

NNRD
ATP-dependent

4

0

High-throughput

0.360

High

1065003

UBR1
E3 ubiquitin-protein ligase UBR1

4

0

High-throughput

0.360

High

1065009

ARB2A
Cotranscriptional regulator ARB2A

4

0

High-throughput

0.360

High

1065028

CA198
Uncharacterized protein C1orf198

4

0

High-throughput

0.360

High

1065038

TSR3
18S rRNA aminocarboxypropyltransferase

4

0

High-throughput

0.360

High

278654

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

3

0

High-throughput

0.347

High

744654

TF2H1
General transcription factor IIH subunit 1

3

0

High-throughput

0.347

High

1005440

RBM6
RNA-binding protein 6

3

0

High-throughput

0.347

High

1041815

CENPC
Centromere protein C

3

0

High-throughput

0.347

High

1064978

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

3

0

High-throughput

0.347

High

1064982

PPR1A
Protein phosphatase 1 regulatory subunit 1A

3

0

High-throughput

0.347

High

1064985

TF2H2
General transcription factor IIH subunit 2

3

0

High-throughput

0.347

High

1064987

MARE2
Microtubule-associated protein RP/EB family member 2

3

0

High-throughput

0.347

High

1064990

C19L2
CWF19-like protein 2

3

0

High-throughput

0.347

High

1064993

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

3

0

High-throughput

0.347

High

1064994

MAP1S
Microtubule-associated protein 1S

3

0

High-throughput

0.347

High

1065000

TEDC2
Tubulin epsilon and delta complex protein 2

3

0

High-throughput

0.347

High

1065004

RAVR1
Ribonucleoprotein PTB-binding 1

3

0

High-throughput

0.347

High

1065006

OGFD1
Prolyl 3-hydroxylase OGFOD1

3

0

High-throughput

0.347

High

1065008

NEUA
N-acylneuraminate cytidylyltransferase

3

0

High-throughput

0.347

High

1065013

ARHG2
Rho guanine nucleotide exchange factor 2

3

0

High-throughput

0.347

High

1065015

BORC6
BLOC-1-related complex subunit 6

3

0

High-throughput

0.347

High

1065020

TCF25
Ribosome quality control complex subunit TCF25

3

0

High-throughput

0.347

High

1065022

TB10A
TBC1 domain family member 10A

3

0

High-throughput

0.347

High

1065029

STPAP
Speckle targeted PIP5K1A-regulated poly(A) polymerase

3

0

High-throughput

0.347

High

1065032

SPS2L
SPATS2-like protein

3

0

High-throughput

0.347

High

1065034

DCA16
DDB1- and CUL4-associated factor 16

3

0

High-throughput

0.347

High

1065036

NPS3A
Protein NipSnap homolog 3A

3

0

High-throughput

0.347

High

1065001

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

2

0

High-throughput

0.318

High

1065014

BORC5
BLOC-1-related complex subunit 5

2

0

High-throughput

0.318

High

1065018

ATX2
Ataxin-2

2

0

High-throughput

0.318

High

1065026

MMAD
Cobalamin trafficking protein CblD

2

0

High-throughput

0.318

High

786078

LONM
Lon protease homolog, mitochondrial

2

0

High-throughput

0.313

High

1064986

TF2H3
General transcription factor IIH subunit 3

2

0

High-throughput

0.298

High

839547

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

846064

GLP1R
Glucagon-like peptide 1 receptor

1

0

Small-scale

0.251

Low

1065019

DPYL5
Dihydropyrimidinase-related protein 5

1

0

High-throughput

0.249

Low

338322

SC24A
Protein transport protein Sec24A

1

0

High-throughput

0.232

Low

1064988

CIP4
Cdc42-interacting protein 4

1

0

High-throughput

0.232

Low

1064995

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.232

Low

1064996

TENS3
Tensin-3

1

0

High-throughput

0.232

Low

1065023

SRXN1
Sulfiredoxin-1

1

0

High-throughput

0.232

Low

1065030

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.232

Low

1065042

LIMC1
LIM and calponin homology domains-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025