Protein: FBX11
F-box only protein 11 (Protein arginine N-methyltransferase 9) (Vitiligo-associated protein 1) (VIT-1)

Gene: FBX11, FBXO11
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q86XK2

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992244

SKP1
S-phase kinase-associated protein 1

14

3

Small-scale

0.984

High

1112584

CUL1
Cullin-1

10

4

Small-scale

0.975

High

1293781

FBX11
F-box only protein 11

1

1

Small-scale

0.710

High

1293815

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

4

1

High-throughput

0.699

High

1293795

FOXJ1
Forkhead box protein J1

4

2

High-throughput

0.697

High

414140

P53
Cellular tumor antigen p53

3

1

Small-scale

0.683

High

156051

SOCS6
Suppressor of cytokine signaling 6

3

1

High-throughput

0.667

High

584116

FOSL2
Fos-related antigen 2

3

2

High-throughput

0.667

High

983871

RBX1
E3 ubiquitin-protein ligase RBX1

4

0

Small-scale

0.667

High

1103259

CTBP1
C-terminal-binding protein 1

4

0

Small-scale

0.664

High

1293811

ZN692
Zinc finger protein 692

3

3

High-throughput

0.662

High

832741

BCL6
B-cell lymphoma 6 protein

2

2

Small-scale

0.646

High

132144

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

0

High-throughput

0.638

High

156392

HSPB6
Heat shock protein beta-6

3

0

High-throughput

0.638

High

1119683

CDK13
Cyclin-dependent kinase 13

3

0

High-throughput

0.638

High

1293782

SCML4
Sex comb on midleg-like protein 4

3

0

High-throughput

0.638

High

1293810

THAP7
THAP domain-containing protein 7

3

0

High-throughput

0.638

High

69798

ZN785
Zinc finger protein 785

2

2

High-throughput

0.628

High

127700

TR10A
Tumor necrosis factor receptor superfamily member 10A

2

1

High-throughput

0.628

High

171891

ZN263
Zinc finger protein 263

2

4

High-throughput

0.628

High

346029

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.628

High

517669

ZBT48
Zinc finger and BTB domain-containing protein 48

2

1

High-throughput

0.628

High

913145

STAT2
Signal transducer and activator of transcription 2

2

1

High-throughput

0.628

High

1293794

CSN5
COP9 signalosome complex subunit 5

2

2

High-throughput

0.628

High

1293817

IKZF5
Zinc finger protein Pegasus

2

2

High-throughput

0.628

High

1293826

AKIP
Small ribosomal subunit protein mS38

2

1

High-throughput

0.628

High

1293829

DTL
Denticleless protein homolog

2

2

Small-scale

0.624

High

1293835

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.618

High

1248527

KIRR2
Kin of IRRE-like protein 2

3

1

High-throughput

0.609

High

215136

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

0

High-throughput

0.602

High

1272477

CSN6
COP9 signalosome complex subunit 6

2

0

High-throughput

0.602

High

1293787

TCP1L
T-complex protein 10A homolog 1

2

0

High-throughput

0.602

High

1293789

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.602

High

1293809

LBHD1
LBH domain-containing protein 1

2

0

High-throughput

0.602

High

1293821

PRDM5
PR domain zinc finger protein 5

2

0

High-throughput

0.602

High

1293822

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

2

0

High-throughput

0.602

High

350062

SNAI1
Zinc finger protein SNAI1

2

2

Small-scale

0.601

High

786159

LONM
Lon protease homolog, mitochondrial

2

1

High-throughput

0.601

High

958667

CSN2
COP9 signalosome complex subunit 2

2

1

High-throughput

0.601

High

1135441

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

2

1

High-throughput

0.601

High

1293805

KIF2C
Kinesin-like protein KIF2C

2

0

High-throughput

0.576

High

1115284

CUL4B
Cullin-4B

1

4

High-throughput

0.575

High

622632

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

1

High-throughput

0.574

High

1293791

AP3S1
AP-3 complex subunit sigma-1

2

1

High-throughput

0.574

High

396447

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

528295

THIO
Thioredoxin

2

0

Small-scale

0.559

High

749484

C2TA
MHC class II transactivator

2

0

Small-scale

0.559

High

979926

H4
Histone H4

2

0

Small-scale

0.559

High

564016

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

650839

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

Small-scale

0.537

High

1293786

BAHD1
Bromo adjacent homology domain-containing 1 protein

1

0

Small-scale

0.537

High

584028

FOSL1
Fos-related antigen 1

1

3

High-throughput

0.536

High

603665

JUNB
Transcription factor JunB

1

2

High-throughput

0.536

High

704474

MZF1
Myeloid zinc finger 1

1

1

High-throughput

0.536

High

1153638

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

3

High-throughput

0.536

High

1159261

ZNF74
Zinc finger protein 74

1

1

High-throughput

0.536

High

1109559

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

High-throughput

0.513

High

1124484

MAP7
Ensconsin

1

0

High-throughput

0.513

High

1126238

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

0

High-throughput

0.513

High

1201225

SPIN4
Spindlin-4

1

0

High-throughput

0.513

High

1219111

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

0

High-throughput

0.513

High

1281408

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

1293784

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.513

High

1293799

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.513

High

1293804

CSN8
COP9 signalosome complex subunit 8

1

0

High-throughput

0.513

High

1293816

MMAD
Cobalamin trafficking protein CblD

1

0

High-throughput

0.513

High

1293819

CSN7B
COP9 signalosome complex subunit 7b

1

0

High-throughput

0.513

High

1293824

RBM12
RNA-binding protein 12

1

0

High-throughput

0.513

High

1293834

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

0

High-throughput

0.513

High

338736

NPTXR
Neuronal pentraxin receptor

1

1

High-throughput

0.489

High

539675

MBL2
Mannose-binding protein C

1

3

High-throughput

0.489

High

1293818

RDD1
Required for drug-induced death protein 1

1

1

High-throughput

0.489

High

1293837

T3JAM
TRAF3-interacting JNK-activating modulator

1

2

High-throughput

0.489

High

124808

AIP
AH receptor-interacting protein

1

1

Small-scale

0.479

High

285348

EED
Polycomb protein EED

1

4

High-throughput

0.479

High

587725

DESP
Desmoplakin

1

1

Small-scale

0.479

High

1098203

DUS8
Dual specificity protein phosphatase 8

1

3

High-throughput

0.479

High

1161868

DUS5
Dual specificity protein phosphatase 5

1

3

High-throughput

0.479

High

1293792

UBXN4
UBX domain-containing protein 4

1

4

High-throughput

0.479

High

1293803

STAC
SH3 and cysteine-rich domain-containing protein

1

1

High-throughput

0.479

High

1293814

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1293839

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.479

High

282601

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

Small-scale

0.458

High

401089

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

570928

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

577813

PLAK
Junction plakoglobin

1

0

Small-scale

0.458

High

712233

TKT
Transketolase

1

0

High-throughput

0.458

High

719156

MPIP1
M-phase inducer phosphatase 1

1

0

Small-scale

0.458

High

724490

GDIA
Rab GDP dissociation inhibitor alpha

1

0

High-throughput

0.458

High

869056

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

904896

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

952937

ACTB
Actin, cytoplasmic 1

1

0

Small-scale

0.458

High

954854

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.458

High

1004786

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1146726

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1147940

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.458

High

1181250

ZN750
Zinc finger protein 750

1

0

Small-scale

0.458

High

1293785

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.458

High

1293793

TFG
Protein TFG

1

0

High-throughput

0.458

High

1293801

SPB12
Serpin B12

1

0

Small-scale

0.458

High

1293807

H2B1L
Histone H2B type 1-L

1

0

Small-scale

0.458

High

1293808

TBA1C
Tubulin alpha-1C chain

1

0

Small-scale

0.458

High

1293820

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1293827

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

Small-scale

0.458

High

1293832

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1293836

NDRG2
Protein NDRG2

1

0

Small-scale

0.458

High

1056833

FMR1
Fragile X messenger ribonucleoprotein 1

1

2

High-throughput

0.457

High

1293823

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

1251920

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.457

High

430101

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

591321

CD44
CD44 antigen

1

1

High-throughput

0.445

High

1063972

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.445

High

1065673

RBL2
Retinoblastoma-like protein 2

1

1

High-throughput

0.445

High

1293796

PGCB
Brevican core protein

1

2

High-throughput

0.437

High

1293812

EFHD1
EF-hand domain-containing protein D1

1

4

High-throughput

0.437

High

159235

ABLM1
Actin-binding LIM protein 1

1

0

High-throughput

0.426

High

164816

UN13B
Protein unc-13 homolog B

1

0

High-throughput

0.426

High

765679

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

772505

IRS1
Insulin receptor substrate 1

1

0

High-throughput

0.426

High

911294

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.426

High

1095693

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.426

High

1180397

KLH40
Kelch-like protein 40

1

0

High-throughput

0.426

High

1250730

MPRIP
Myosin phosphatase Rho-interacting protein

1

0

High-throughput

0.426

High

1272236

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.426

High

1293783

SYNPO
Synaptopodin

1

0

High-throughput

0.426

High

1293806

ATX2
Ataxin-2

1

0

High-throughput

0.426

High

1293830

VSX1
Visual system homeobox 1

1

0

High-throughput

0.426

High

1293831

CEP72
Centrosomal protein of 72 kDa

1

0

High-throughput

0.426

High

1293841

FHOD1
FH1/FH2 domain-containing protein 1

1

0

High-throughput

0.426

High

1293833

HDAC6
Protein deacetylase HDAC6

1

2

Small-scale

0.408

High

1293840

UBP16
Ubiquitin carboxyl-terminal hydrolase 16

1

0

Small-scale

0.391

High

276217

LRRN2
Leucine-rich repeat neuronal protein 2

2

0

High-throughput

0.328

High

1030833

DEF6
Defensin-6

2

0

High-throughput

0.328

High

1293788

CC107
Coiled-coil domain-containing protein 107

2

0

High-throughput

0.328

High

570691

EDN3
Endothelin-3

2

0

High-throughput

0.313

High

595071

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

0

High-throughput

0.313

High

1293802

SNX18
Sorting nexin-18

2

0

High-throughput

0.313

High

554137

BMP2
Bone morphogenetic protein 2

1

0

High-throughput

0.279

Low

616083

LAG3
Lymphocyte activation gene 3 protein

1

0

High-throughput

0.279

Low

1206599

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.279

Low

1293790

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

1293797

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

1293798

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1293813

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

0

High-throughput

0.279

Low

1293838

SNX24
Sorting nexin-24

1

0

High-throughput

0.279

Low

962978

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

1010662

DCD
Dermcidin

1

0

Small-scale

0.249

Low

1064449

DSC1
Desmocollin-1

1

0

Small-scale

0.249

Low

1194689

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.249

Low

1293825

NECP2
Adaptin ear-binding coat-associated protein 2

1

0

High-throughput

0.249

Low

1293828

Q9NZ23
glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.249

Low

947015

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

616769

SDC1
Syndecan-1

1

0

High-throughput

0.232

Low

1070445

ZNFS1
Putative uncharacterized protein ZNF252P-AS1

1

0

High-throughput

0.232

Low

1211925

S35F1
Solute carrier family 35 member F1

1

0

High-throughput

0.232

Low

1293800

F161B
Protein FAM161B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025