Protein: SHOX2
Short stature homeobox protein 2 (Homeobox protein Og12X) (Paired-related homeobox protein SHOT)

Gene: SHOX2
Organism: Homo sapiens
Interactions: 17
UniProt ID: O60902

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001501 - skeletal system development
GO:0001649 - osteoblast differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

261002

CDK4
Cyclin-dependent kinase 4

1

10

Small-scale

0.550

High

261008

TRI29
Tripartite motif-containing protein 29

1

6

High-throughput

0.541

High

261001

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.515

High

261004

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.515

High

261007

CASP6
Caspase-6

1

2

High-throughput

0.515

High

261010

ZDH17
Palmitoyltransferase ZDHHC17

1

14

High-throughput

0.494

High

261000

WFS1
Wolframin

1

0

High-throughput

0.493

High

261011

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.493

High

261014

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

261013

KDM5B
Lysine-specific demethylase 5B

1

4

Small-scale

0.479

High

260999

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.470

High

245824

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

261003

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

261005

GRN
Progranulin

1

0

High-throughput

0.268

Low

261006

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.268

Low

261009

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

261012

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025