Protein: PLCZ1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-zeta-1) (Phospholipase C-zeta-1) (PLC-zeta-1) (Testis-development protein NYD-SP27)

Gene: PLCZ1
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q86YW0

Gene Ontology (top 5):
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0005509 - calcium ion binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

407870

SEMG1
Semenogelin-1

3

0

High-throughput

0.638

High

1295661

SPA12
Serpin A12

3

1

High-throughput

0.609

High

839582

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.585

High

652350

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

2

High-throughput

0.536

High

447188

NPM
Nucleophosmin

1

1

High-throughput

0.515

High

276604

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.513

High

571467

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.493

High

995678

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.493

High

1295662

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

380763

HBD
Hemoglobin subunit delta

1

0

High-throughput

0.458

High

842427

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

998506

H31
Histone H3.1

1

0

High-throughput

0.458

High

892116

KLK7
Kallikrein-7

3

0

High-throughput

0.347

High

1154319

CYTM
Cystatin-M

2

0

High-throughput

0.318

High

1159393

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025