Protein: ERAP2
Endoplasmic reticulum aminopeptidase 2 (EC 3.4.11.-) (Leukocyte-derived arginine aminopeptidase) (L-RAP)

Gene: ERAP2
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q6P179

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0002474 - antigen processing and presentation of peptide antigen via MHC class I
GO:0004175 - endopeptidase activity
GO:0004177 - aminopeptidase activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

961319

RL27
Large ribosomal subunit protein eL27

3

1

High-throughput

0.650

High

1240566

FBX2
F-box only protein 2

1

6

High-throughput

0.536

High

293856

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

533944

IRF1
Interferon regulatory factor 1

1

2

Small-scale

0.479

High

535189

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

566713

PDIA4
Protein disulfide-isomerase A4

1

3

High-throughput

0.479

High

695726

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

820674

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.479

High

951214

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

1098419

DNJC3
DnaJ homolog subfamily C member 3

1

8

High-throughput

0.479

High

1240554

SYNE3
Nesprin-3

1

2

High-throughput

0.479

High

1240555

DJC10
DnaJ homolog subfamily C member 10

1

8

High-throughput

0.479

High

1240556

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1240557

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.479

High

1240559

CALR3
Calreticulin-3

1

5

High-throughput

0.479

High

1240561

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

1240562

FBX6
F-box only protein 6

1

6

High-throughput

0.479

High

1240564

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

1240565

DJB11
DnaJ homolog subfamily B member 11

1

3

High-throughput

0.479

High

1240567

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

1141699

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

1179098

TECT1
Tectonic-1

1

0

High-throughput

0.458

High

571615

IRF2
Interferon regulatory factor 2

1

2

Small-scale

0.437

High

588939

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

768444

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

941466

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.437

High

1240560

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

9

High-throughput

0.437

High

1240558

MFSD3
Major facilitator superfamily domain-containing protein 3

1

0

High-throughput

0.426

High

1240563

S22AB
Solute carrier family 22 member 11

1

5

High-throughput

0.407

High

958970

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

653387

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025