Protein: S22AB
Solute carrier family 22 member 11 (Organic anion transporter 4) (OAT4) (Organic anion:dicarboxylate exchanger OAT4)

Gene: S22AB, SLC22A11
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q9NSA0

Gene Ontology (top 5):
GO:0005452 - solute:inorganic anion antiporter activity
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0008514 - organic anion transmembrane transporter activity
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1400031

NED4L
E3 ubiquitin-protein ligase NEDD4-like

2

8

Small-scale

0.584

High

1130477

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

1

Small-scale

0.489

High

249064

NRP2
Neuropilin-2

1

4

High-throughput

0.445

High

345010

WIZ
Protein Wiz

1

2

High-throughput

0.445

High

441513

AGAL
Alpha-galactosidase A

1

1

High-throughput

0.445

High

714656

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

5

High-throughput

0.445

High

877391

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.445

High

938630

PSA
Puromycin-sensitive aminopeptidase

1

5

High-throughput

0.445

High

947484

RAB15
Ras-related protein Rab-15

1

1

High-throughput

0.445

High

958361

ARP2
Actin-related protein 2

1

1

High-throughput

0.445

High

1008457

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

2

High-throughput

0.445

High

1054336

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

1

High-throughput

0.445

High

1204809

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

2

High-throughput

0.445

High

1277529

MON2
Protein MON2 homolog

1

2

High-throughput

0.445

High

1316777

WDFY3
WD repeat and FYVE domain-containing protein 3

1

2

High-throughput

0.445

High

1324687

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

1

1

High-throughput

0.445

High

1394133

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.445

High

1394684

KIRR1
Kin of IRRE-like protein 1

1

2

High-throughput

0.445

High

1438178

RHOF
Rho-related GTP-binding protein RhoF

1

11

High-throughput

0.445

High

1449278

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

5

High-throughput

0.445

High

1449279

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.445

High

1449280

NOTC3
Neurogenic locus notch homolog protein 3

1

3

High-throughput

0.445

High

1449282

PLAP
Phospholipase A-2-activating protein

1

1

High-throughput

0.445

High

1449283

EFR3B
Protein EFR3 homolog B

1

1

High-throughput

0.445

High

1449284

RAP2C
Ras-related protein Rap-2c

1

2

High-throughput

0.445

High

775333

FUS
RNA-binding protein FUS

1

1

High-throughput

0.437

High

186809

P73
Tumor protein p73

1

0

High-throughput

0.426

High

316632

ST17B
Serine/threonine-protein kinase 17B

1

0

High-throughput

0.426

High

337033

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.426

High

488874

FURIN
Furin

1

0

High-throughput

0.426

High

637961

NF1
Neurofibromin

1

0

High-throughput

0.426

High

644564

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.426

High

712288

TKT
Transketolase

1

0

High-throughput

0.426

High

720135

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

High-throughput

0.426

High

868106

AL1A3
Retinaldehyde dehydrogenase 3

1

0

High-throughput

0.426

High

896900

DYN2
Dynamin-2

1

0

High-throughput

0.426

High

903005

MMP15
Matrix metalloproteinase-15

1

0

High-throughput

0.426

High

914067

SPSY
Spermine synthase

1

0

High-throughput

0.426

High

921804

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

1007611

PRAME
Melanoma antigen preferentially expressed in tumors

1

0

High-throughput

0.426

High

1025852

BORG5
Cdc42 effector protein 1

1

0

High-throughput

0.426

High

1038365

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

0

High-throughput

0.426

High

1209017

TTC38
Tetratricopeptide repeat protein 38

1

0

High-throughput

0.426

High

1217207

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.426

High

1224712

TSH3
Teashirt homolog 3

1

0

High-throughput

0.426

High

1353107

ARH40
Rho guanine nucleotide exchange factor 40

1

0

High-throughput

0.426

High

1360623

MADD
MAP kinase-activating death domain protein

1

0

High-throughput

0.426

High

1396214

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.426

High

1449285

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.426

High

1449286

PCDGH
Protocadherin gamma-B5

1

0

High-throughput

0.426

High

220026

XRCC3
DNA repair protein XRCC3

1

2

High-throughput

0.407

High

245544

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

1

High-throughput

0.407

High

245746

GANP
Germinal-center associated nuclear protein

1

1

High-throughput

0.407

High

273235

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

1

High-throughput

0.407

High

295543

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

4

High-throughput

0.407

High

302978

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

1

High-throughput

0.407

High

405349

OAT
Ornithine aminotransferase, mitochondrial

1

1

High-throughput

0.407

High

431411

AT5G1
ATP synthase F(0) complex subunit C1, mitochondrial

1

1

High-throughput

0.407

High

600519

ZNF3
Zinc finger protein 3

1

1

High-throughput

0.407

High

611698

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

1

High-throughput

0.407

High

662808

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

3

High-throughput

0.407

High

755638

TTK
Dual specificity protein kinase TTK

1

2

High-throughput

0.407

High

930371

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

1

High-throughput

0.407

High

945868

EPIPL
Epiplakin

1

1

High-throughput

0.407

High

1009770

M3K9
Mitogen-activated protein kinase kinase kinase 9

1

1

High-throughput

0.407

High

1052380

RN5A
2-5A-dependent ribonuclease

1

3

High-throughput

0.407

High

1090562

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

8

High-throughput

0.407

High

1102269

ATM
Serine-protein kinase ATM

1

3

High-throughput

0.407

High

1109515

ATR
Serine/threonine-protein kinase ATR

1

3

High-throughput

0.407

High

1131900

COG2
Conserved oligomeric Golgi complex subunit 2

1

1

High-throughput

0.407

High

1138895

SYLM
Leucine--tRNA ligase, mitochondrial

1

2

High-throughput

0.407

High

1161233

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.407

High

1200284

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

1

High-throughput

0.407

High

1206252

PREP
Presequence protease, mitochondrial

1

1

High-throughput

0.407

High

1210628

SYVM
Valine--tRNA ligase, mitochondrial

1

2

High-throughput

0.407

High

1216532

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

1

High-throughput

0.407

High

1240563

ERAP2
Endoplasmic reticulum aminopeptidase 2

1

5

High-throughput

0.407

High

1242098

TTC27
Tetratricopeptide repeat protein 27

1

5

High-throughput

0.407

High

1244379

SKI3
Superkiller complex protein 3

1

3

High-throughput

0.407

High

1288049

PRP39
Pre-mRNA-processing factor 39

1

1

High-throughput

0.407

High

1315931

RASEF
Ras and EF-hand domain-containing protein

1

2

High-throughput

0.407

High

1315954

CHSS2
Chondroitin sulfate synthase 2

1

3

High-throughput

0.407

High

1338118

NAV1
Neuron navigator 1

1

1

High-throughput

0.407

High

1351317

DMXL2
DmX-like protein 2

1

2

High-throughput

0.407

High

1360183

RUFY2
RUN and FYVE domain-containing protein 2

1

3

High-throughput

0.407

High

1360577

ATLA1
Atlastin-1

1

4

High-throughput

0.407

High

1361419

PPM1E
Protein phosphatase 1E

1

1

High-throughput

0.407

High

1365515

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

3

High-throughput

0.407

High

1370913

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

1

High-throughput

0.407

High

1388867

HOOK2
Protein Hook homolog 2

1

2

High-throughput

0.407

High

1401324

PASK
PAS domain-containing serine/threonine-protein kinase

1

2

High-throughput

0.407

High

1403354

RUFY1
RUN and FYVE domain-containing protein 1

1

3

High-throughput

0.407

High

1412543

GCP2
Gamma-tubulin complex component 2

1

1

High-throughput

0.407

High

1420142

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

3

High-throughput

0.407

High

1435158

ESRP2
Epithelial splicing regulatory protein 2

1

1

High-throughput

0.407

High

1437475

RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial

1

2

High-throughput

0.407

High

1437774

XPO5
Exportin-5

1

7

High-throughput

0.407

High

1449274

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

1

High-throughput

0.407

High

1449281

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

1

High-throughput

0.407

High

1449287

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

2

High-throughput

0.407

High

64135

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.232

Low

137278

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.232

Low

177315

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.232

Low

177476

ZN536
Zinc finger protein 536

1

0

High-throughput

0.232

Low

187566

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.232

Low

214627

WDR62
WD repeat-containing protein 62

1

0

High-throughput

0.232

Low

252922

EXOC3
Exocyst complex component 3

1

0

High-throughput

0.232

Low

290170

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.232

Low

451283

NFL
Neurofilament light polypeptide

1

0

High-throughput

0.232

Low

608199

PYRG1
CTP synthase 1

1

0

High-throughput

0.232

Low

789231

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.232

Low

793772

ETFB
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.232

Low

1083772

MPPA
Mitochondrial-processing peptidase subunit alpha

1

0

High-throughput

0.232

Low

1121605

URB2
Unhealthy ribosome biogenesis protein 2 homolog

1

0

High-throughput

0.232

Low

1140240

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.232

Low

1149472

SKI2
Superkiller complex protein 2

1

0

High-throughput

0.232

Low

1163708

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

0

High-throughput

0.232

Low

1205151

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.232

Low

1207157

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

1224781

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.232

Low

1228946

CRBG3
Very large A-kinase anchor protein

1

0

High-throughput

0.232

Low

1230764

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.232

Low

1239311

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.232

Low

1245228

BRAT1
Integrator complex assembly factor BRAT1

1

0

High-throughput

0.232

Low

1248293

MOXD1
DBH-like monooxygenase protein 1

1

0

High-throughput

0.232

Low

1251564

THADA
tRNA

1

0

High-throughput

0.232

Low

1295657

HPS6
BLOC-2 complex member HPS6

1

0

High-throughput

0.232

Low

1323846

INT1
Integrator complex subunit 1

1

0

High-throughput

0.232

Low

1325281

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.232

Low

1356163

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

High-throughput

0.232

Low

1365915

NU205
Nuclear pore complex protein Nup205

1

0

High-throughput

0.232

Low

1385755

INT12
Integrator complex subunit 12

1

0

High-throughput

0.232

Low

1393048

PDLI5
PDZ and LIM domain protein 5

1

0

High-throughput

0.232

Low

1393901

DHTK1
2-oxoadipate dehydrogenase complex component E1

1

0

High-throughput

0.232

Low

1395571

SRAC1
Protein SERAC1

1

0

High-throughput

0.232

Low

1406574

METH
Methionine synthase

1

0

High-throughput

0.232

Low

1413867

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.232

Low

1419179

STK33
Serine/threonine-protein kinase 33

1

0

High-throughput

0.232

Low

1420799

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.232

Low

1434526

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.232

Low

1437031

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.232

Low

1449275

MDN1
Midasin

1

0

High-throughput

0.232

Low

1449276

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.232

Low

1449277

PANK4
4'-phosphopantetheine phosphatase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025