HitPredict

Interactor 1: ARHGI (Q6ZSZ5)
Rho guanine nucleotide exchange factor 18 (114 kDa Rho-specific guanine nucleotide exchange factor) (p114-Rho-GEF) (p114RhoGEF) (Septin-associated RhoGEF) (SA-RhoGEF)
Gene: ARHGEF18

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RhoGEF~fn3
Common GO terms	GO:0005856 - cytoskeleton GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1361 Hs			1 783
+	Hs
		1086369 AKP13_HUMAN (326-1282): 2.21e-97: 348: 35.64		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1254920 ARHG2_HUMAN (258-1247): 7.76e-90: 316: 30.17		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		177388 ARHGB_HUMAN (251-1002): 1.77e-86: 312: 17.81		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		587706 DESP_HUMAN (378-1165): 3.4e-84: 307: 15.04		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1154110 ITSN1_HUMAN (355-820): 3.46e-79: 290: 18.76		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1121959 ARHG7_HUMAN (233-996): 3.37e-76: 272: 12.58		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1140178 ARHG6_HUMAN (300-1036): 1.02e-73: 264: 13.03		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1254908 ARHG1_HUMAN (243-955): 3.42e-72: 262: 21.26		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1254765 PREX1_HUMAN (405-1221): 1.69e-69: 259: 11.80		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		913659 VAV2_HUMAN (361-820): 6.75e-69: 252: 15.45		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1255867 ARHGC_HUMAN (244-948): 2.05e-66: 249: 18.24		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		213362 ARHG9_HUMAN (371-860): 5.39e-69: 243: 13.24		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		320566 FARP2_HUMAN (230-878): 8.87e-65: 242: 14.66		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		238820 KALRN_HUMAN (60-1039): 9.97e-57: 219: 11.61		TRI67_HUMAN (1-783): 0: 595: 100.00
+	Hs
		1371071 ARHG2_HUMAN (258-1247): 7.76e-90: 316: 30.17		TRI36_HUMAN (112-771): 4.44e-106: 343: 20.13
+	Hs
		1253656 PKHG7_HUMAN (158-808): 4.85e-78: 275: 15.97		TRIM7_HUMAN (190-762): 7.85e-85: 280: 15.75
+	Hs
		1140194 ARHG6_HUMAN (300-1036): 1.02e-73: 264: 13.03		TRI54_HUMAN (198-528): 1.12e-73: 245: 20.71
+	Hs
		587554 DESP_HUMAN (378-1165): 3.4e-84: 307: 15.04		RO52_HUMAN (112-378): 2.43e-12: 72: 9.29
+	Hs
		572235 ARHG3_HUMAN (326-825): 3.3e-81: 279: 17.34		TRI27_HUMAN (104-639): 1.21e-12: 73.2: 12.20
+	Hs
		213352 ARHG9_HUMAN (371-860): 5.39e-69: 243: 13.24		RO52_HUMAN (112-378): 2.43e-12: 72: 9.29