HitPredict

Interactor 1: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Interactor 2: PPIP2 (Q9H939)
Proline-serine-threonine phosphatase-interacting protein 2 (PEST phosphatase-interacting protein 2)
Gene: PSTPIP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	27880917, 28514442, 28675297, 31980649, 33961781, unassigned2173
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 780 Hs			1 334
+	Hs
		207795 PTN12_HUMAN (1-780): 0: 586: 100.00		PPIP1_HUMAN (1-332): 1.09e-78: 248: 43.62
+	Mm
		728830 PTN12_MOUSE (1-780): 0: 560: 83.10		PPIP2_MOUSE (1-334): 5.19e-88: 269: 87.43
+	Mm
		728826 PTN12_MOUSE (1-780): 0: 560: 83.10		PPIP1_MOUSE (1-324): 1.22e-78: 247: 44.07
+	Mm
		666001 PTN22_MOUSE (1-779): 1.51e-143: 443: 32.93		PPIP2_MOUSE (1-334): 5.19e-88: 269: 87.43
+	Mm
		665999 PTN22_MOUSE (1-779): 1.51e-143: 443: 32.93		PPIP1_MOUSE (1-324): 1.22e-78: 247: 44.07
+	Hs
		1333999 PTN22_HUMAN (1-779): 6.27e-132: 413: 32.01		PPIP2_HUMAN (1-334): 5.98e-88: 268: 100.00
+	Mm
		1142213 PTN18_MOUSE (2-446): 8.05e-136: 411: 32.97		PPIP2_MOUSE (1-334): 5.19e-88: 269: 87.43
+	Hs
		207851 PTN22_HUMAN (1-779): 6.27e-132: 413: 32.01		PPIP1_HUMAN (1-332): 1.09e-78: 248: 43.62
+	Mm
		956955 PTN18_MOUSE (2-446): 8.05e-136: 411: 32.97		PPIP1_MOUSE (1-324): 1.22e-78: 247: 44.07
+	Hs
		1307332 PTN18_HUMAN (14-446): 4.35e-123: 378: 32.66		PPIP2_HUMAN (1-334): 5.98e-88: 268: 100.00
+	Hs
		207769 PTN1_HUMAN (27-409): 1.5e-127: 389: 24.46		PPIP1_HUMAN (1-332): 1.09e-78: 248: 43.62
+	Hs
		207829 PTN18_HUMAN (14-446): 4.35e-123: 378: 32.66		PPIP1_HUMAN (1-332): 1.09e-78: 248: 43.62
+	Hs
		617105 PTPRG_HUMAN (8-299): 1.84e-52: 200: 24.50		FCHO2_HUMAN (1-327): 4.83e-71: 237: 18.26