Protein: DHOM
Homoserine dehydrogenase (HDH) (EC 1.1.1.3)

Gene: DHOM, HOM6
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P31116

Gene Ontology (top 5):
GO:0004072 - aspartate kinase activity
GO:0004412 - homoserine dehydrogenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0009067 - aspartate family amino acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678210

DHOM
Homoserine dehydrogenase

2

1

Small-scale

0.737

High

543348

HSC82
ATP-dependent molecular chaperone HSC82

3

2

High-throughput

0.643

High

510537

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

678221

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.513

High

627781

SIS1
Protein SIS1

1

0

High-throughput

0.493

High

584676

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.479

High

586372

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.479

High

678218

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.479

High

678230

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.479

High

334451

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.479

High

342679

ENO1
Enolase 1

1

1

High-throughput

0.479

High

365938

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.479

High

340634

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

343366

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

389247

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

410943

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

537373

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

540540

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.458

High

661559

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

678211

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

678216

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

678219

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

678223

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

678224

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

678226

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

678228

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

678229

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

678232

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

678233

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

678222

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

342885

ENO2
Enolase 2

1

1

High-throughput

0.437

High

678217

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.437

High

367828

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

493402

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

560588

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

678225

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

Small-scale

0.251

Low

343561

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.249

Low

520935

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

678212

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.249

Low

678213

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

678214

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.249

Low

678220

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

678227

MTM1
Mitochondrial carrier protein MTM1

1

0

High-throughput

0.249

Low

678231

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

566543

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.232

Low

678215

CTM1
Cytochrome c lysine N-methyltransferase 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024