Protein: ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)]

Gene: ASML, ASMTL
Organism: Homo sapiens
Interactions: 46
UniProt ID: O95671

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0008171 - O-methyltransferase activity
GO:0009117 - nucleotide metabolic process
GO:0032259 - methylation
GO:0036218 - dTTP diphosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341229

ASML
Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase

2

5

High-throughput

0.815

High

341240

T23O
Tryptophan 2,3-dioxygenase

7

0

High-throughput

0.721

High

341248

K1H1
Keratin, type I cuticular Ha1

3

2

High-throughput

0.675

High

300276

KRT34
Keratin, type I cuticular Ha4

2

2

High-throughput

0.606

High

341250

WDR44
WD repeat-containing protein 44

2

0

High-throughput

0.602

High

240387

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

341243

REL
Proto-oncogene c-Rel

2

0

High-throughput

0.580

High

341251

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.573

High

341262

OPTN
Optineurin

1

1

High-throughput

0.515

High

211467

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

1

0

High-throughput

0.513

High

274420

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

341246

MAP7
Ensconsin

1

0

High-throughput

0.513

High

341247

IRF3
Interferon regulatory factor 3

1

0

High-throughput

0.513

High

341264

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

341245

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.493

High

341230

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

341244

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

341234

PIM1
Serine/threonine-protein kinase pim-1

1

0

High-throughput

0.426

High

341256

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.426

High

341260

SETD6
N-lysine methyltransferase SETD6

1

0

High-throughput

0.426

High

341263

AURKB
Aurora kinase B

1

0

High-throughput

0.426

High

341233

CEL3A
Chymotrypsin-like elastase family member 3A

1

1

High-throughput

0.407

High

341236

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.407

High

341237

ACKR3
Atypical chemokine receptor 3

1

1

High-throughput

0.407

High

341241

CXCR3
C-X-C chemokine receptor type 3

1

1

High-throughput

0.407

High

341249

KLH40
Kelch-like protein 40

2

0

High-throughput

0.328

High

341257

CFA52
Cilia- and flagella-associated protein 52

2

0

High-throughput

0.328

High

341261

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

0

High-throughput

0.328

High

341258

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High

341265

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.316

High

341259

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.299

High

341235

DRB4
HLA class II histocompatibility antigen, DR beta 4 chain

1

0

High-throughput

0.282

High

289344

CTAG2
Cancer/testis antigen 2

1

0

High-throughput

0.279

Low

341238

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

341252

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

341255

CLC14
C-type lectin domain family 14 member A

1

0

High-throughput

0.279

Low

341266

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

341267

RPKL1
Ribosomal protein S6 kinase-like 1

1

0

High-throughput

0.279

Low

105028

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

341253

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

341254

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

341231

INHA
Inhibin alpha chain

1

0

High-throughput

0.232

Low

341232

HEPS
Serine protease hepsin

1

0

High-throughput

0.232

Low

341239

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

341242

S26A5
Prestin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025