Protein: SYNRG
Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin)

Gene: SYNRG
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q9UMZ2

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0006886 - intracellular protein transport
GO:0006897 - endocytosis
GO:0030121 - AP-1 adaptor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

225866

AP1G1
AP-1 complex subunit gamma-1

4

4

Small-scale

0.694

High

333256

VAPB
Vesicle-associated membrane protein-associated protein B/C

4

1

High-throughput

0.691

High

1460812

GGA1
ADP-ribosylation factor-binding protein GGA1

4

3

Small-scale

0.678

High

940575

AP1S2
AP-1 complex subunit sigma-2

3

1

High-throughput

0.675

High

295772

AP1G2
AP-1 complex subunit gamma-like 2

3

4

Small-scale

0.669

High

170430

AURKA
Aurora kinase A

3

1

High-throughput

0.667

High

946221

MLF1
Myeloid leukemia factor 1

4

0

High-throughput

0.661

High

1366003

APBP2
Amyloid protein-binding protein 2

3

0

High-throughput

0.646

High

1248021

AFTIN
Aftiphilin

2

0

Small-scale

0.585

High

976662

RB11A
Ras-related protein Rab-11A

2

1

High-throughput

0.584

High

1453845

VAPA
Vesicle-associated membrane protein-associated protein A

2

1

High-throughput

0.574

High

1460804

GGA2
ADP-ribosylation factor-binding protein GGA2

1

4

Small-scale

0.561

High

909243

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.536

High

1083336

AP1B1
AP-1 complex subunit beta-1

1

3

High-throughput

0.536

High

1399539

AP1S3
AP-1 complex subunit sigma-3

1

1

High-throughput

0.536

High

530575

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

1462127

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

0

High-throughput

0.513

High

1462128

AP1M2
AP-1 complex subunit mu-2

1

0

High-throughput

0.513

High

178860

SCAM1
Secretory carrier-associated membrane protein 1

1

0

Small-scale

0.504

High

1108282

SQSTM
Sequestosome-1

1

0

High-throughput

0.493

High

173551

XPO1
Exportin-1

1

1

High-throughput

0.479

High

483259

CLCA
Clathrin light chain A

1

1

High-throughput

0.479

High

483418

CLCB
Clathrin light chain B

1

1

High-throughput

0.479

High

631019

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.479

High

641283

FGFR2
Fibroblast growth factor receptor 2

1

1

High-throughput

0.479

High

648739

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.479

High

691535

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

730349

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.479

High

730955

1433S
14-3-3 protein sigma

1

6

High-throughput

0.479

High

891356

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.479

High

891882

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

945120

RAB25
Ras-related protein Rab-25

1

1

High-throughput

0.479

High

967018

1433G
14-3-3 protein gamma

1

6

High-throughput

0.479

High

989167

AP2B1
AP-2 complex subunit beta

1

4

High-throughput

0.479

High

990867

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.479

High

1049904

1433F
14-3-3 protein eta

1

6

High-throughput

0.479

High

1251980

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.479

High

1460296

XPO7
Exportin-7

1

1

High-throughput

0.479

High

189925

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

218958

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

226260

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

346497

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

459799

PROF1
Profilin-1

1

0

High-throughput

0.458

High

714522

PML
Protein PML

1

0

High-throughput

0.458

High

972126

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.458

High

991961

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1252294

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1276370

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1291605

HOOK3
Protein Hook homolog 3

1

0

High-throughput

0.458

High

1324929

RHG18
Rho GTPase-activating protein 18

1

0

High-throughput

0.458

High

1356339

SMAP2
Stromal membrane-associated protein 2

1

0

High-throughput

0.458

High

1429015

WWTR1
WW domain-containing transcription regulator protein 1

1

0

High-throughput

0.458

High

1432913

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

0

Small-scale

0.458

High

1454495

HTR5B
HEAT repeat-containing protein 5B

1

0

Small-scale

0.458

High

1459306

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1461976

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.458

High

318912

RHBT1
Rho-related BTB domain-containing protein 1

1

1

High-throughput

0.437

High

1251897

CCNI2
Cyclin-I2

1

0

High-throughput

0.426

High

1452997

GGA3
ADP-ribosylation factor-binding protein GGA3

1

4

Small-scale

0.408

High

281456

GGYF1
GRB10-interacting GYF protein 1

1

0

High-throughput

0.279

Low

1452891

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.279

Low

1459561

GCP4
Gamma-tubulin complex component 4

1

0

High-throughput

0.279

Low

896664

VASP
Vasodilator-stimulated phosphoprotein

1

0

High-throughput

0.249

Low

1156621

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.249

Low

1233573

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1276964

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1289720

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1327268

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1348005

DPTOR
DEP domain-containing mTOR-interacting protein

1

0

Small-scale

0.249

Low

1428421

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.249

Low

946647

S26A5
Prestin

1

0

High-throughput

0.232

Low

1010985

BAT1
b(0,+)-type amino acid transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025