Protein: CG22
G2/mitotic-specific cyclin-2

Gene: CG22, CLB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P24869

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001932 - regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

339458

CDK1
Cyclin-dependent kinase 1

30

20

Small-scale

0.993

High

624678

SWE1
Mitosis inhibitor protein kinase SWE1

6

11

Small-scale

0.948

High

624704

CDH1
APC/C activator protein CDH1

11

20

Small-scale

0.756

High

594110

CKS1
Cyclin-dependent kinases regulatory subunit

8

20

Small-scale

0.746

High

624682

SIC1
Protein SIC1

6

5

Small-scale

0.727

High

447783

CDC6
Cell division control protein 6

5

9

Small-scale

0.711

High

624667

NAP1
Nucleosome assembly protein

3

2

Small-scale

0.674

High

624674

CDC20
APC/C activator protein CDC20

3

20

Small-scale

0.656

High

624669

KIN82
Serine/threonine-protein kinase KIN82

1

3

High-throughput

0.647

High

624687

IPL1
Spindle assembly checkpoint kinase

1

3

Small-scale

0.647

High

624671

BUD3
Bud site selection protein 3

3

0

Small-scale

0.621

High

624709

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

4

High-throughput

0.621

High

624723

NDD1
Nuclear division defective protein 1

2

1

Small-scale

0.620

High

565464

PHO85
Cyclin-dependent protein kinase PHO85

1

20

Small-scale

0.618

High

602621

MCK1
Protein kinase MCK1

1

20

Small-scale

0.618

High

605484

DBF2
Cell cycle protein kinase DBF2

1

7

Small-scale

0.618

High

624650

CG21
G2/mitotic-specific cyclin-1

1

6

Small-scale

0.618

High

624716

STE20
Serine/threonine-protein kinase STE20

1

6

Small-scale

0.618

High

624668

SWI4
Regulatory protein SWI4

2

2

Small-scale

0.612

High

624702

NET1
Nucleolar protein NET1

2

2

Small-scale

0.602

High

624714

IMA1
Importin subunit alpha

2

2

Small-scale

0.595

High

624686

HAL5
Serine/threonine-protein kinase HAL5

1

7

High-throughput

0.579

High

561110

CDC23
Anaphase-promoting complex subunit CDC23

1

8

Small-scale

0.573

High

624692

SSB2
Ribosome-associated molecular chaperone SSB2

2

11

Small-scale

0.571

High

624684

ORC6
Origin recognition complex subunit 6

1

1

Small-scale

0.569

High

624717

FIN1
Filament protein FIN1

1

1

Small-scale

0.569

High

624680

ASK1
DASH complex subunit ASK1

1

0

Small-scale

0.545

High

624681

SLI15
Inner centromere protein-related protein SLI15

1

0

Small-scale

0.545

High

624691

GLE2
mRNA export factor GLE2

1

1

High-throughput

0.536

High

624695

NU159
Nucleoporin NUP159

1

4

High-throughput

0.536

High

624688

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.513

High

624693

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.513

High

624713

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.513

High

624715

MUK1
Protein MUK1

1

0

High-throughput

0.513

High

622136

MCM3
DNA replication licensing factor MCM3

1

5

Small-scale

0.501

High

624700

ECO1
N-acetyltransferase ECO1

1

1

Small-scale

0.501

High

624703

APC10
Anaphase-promoting complex subunit DOC1

1

1

Small-scale

0.501

High

541844

NSP1
Nucleoporin NSP1

1

6

High-throughput

0.489

High

624711

NU100
Nucleoporin NUP100/NSP100

1

6

High-throughput

0.489

High

624712

NU116
Nucleoporin NUP116/NSP116

1

6

High-throughput

0.489

High

589264

FKBP
FK506-binding protein 1

1

0

High-throughput

0.486

High

624683

NEL1
GTPase-activating protein NEL1

1

0

High-throughput

0.486

High

624718

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.486

High

624719

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.486

High

624690

FIR1
Factor interacting with REF2

1

4

Small-scale

0.481

High

624721

CYK2
Cytokinesis protein 2

1

1

Small-scale

0.481

High

539916

RAD9
DNA repair protein RAD9

1

0

Small-scale

0.480

High

624705

H1
Histone H1

1

0

Small-scale

0.480

High

624670

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.479

High

402885

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

Small-scale

0.479

High

415894

DED1
ATP-dependent RNA helicase DED1

1

2

Small-scale

0.479

High

431343

LTE1
Guanine nucleotide exchange factor LTE1

1

1

Small-scale

0.479

High

449919

HSP73
Heat shock protein SSA3

1

8

Small-scale

0.479

High

490414

HSP71
Heat shock protein SSA1

1

8

Small-scale

0.479

High

493257

HSP72
Heat shock protein SSA2

1

8

Small-scale

0.479

High

510339

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

Small-scale

0.479

High

597113

ACE2
Metallothionein expression activator

1

5

Small-scale

0.479

High

597562

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

2

Small-scale

0.479

High

605298

HSP74
Heat shock protein SSA4

1

8

Small-scale

0.479

High

624207

DBP1
ATP-dependent RNA helicase DBP1

1

2

Small-scale

0.479

High

624673

SYP1
Suppressor of yeast profilin deletion

1

1

Small-scale

0.479

High

624675

HIR1
Protein HIR1

1

1

Small-scale

0.479

High

624676

HIR2
Protein HIR2

1

1

Small-scale

0.479

High

624677

STE5
Protein STE5

1

1

Small-scale

0.479

High

624679

PRS7
26S proteasome regulatory subunit 7 homolog

1

2

Small-scale

0.479

High

624685

KEL1
Kelch repeat-containing protein 1

1

2

Small-scale

0.479

High

624694

FKH1
Fork head protein homolog 1

1

4

Small-scale

0.479

High

624697

FKH2
Fork head protein homolog 2

1

5

Small-scale

0.479

High

624698

MPG1
Mannose-1-phosphate guanyltransferase

1

1

Small-scale

0.479

High

624701

COM1
DNA endonuclease SAE2

1

1

Small-scale

0.479

High

624710

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

Small-scale

0.479

High

367763

EF1A
Elongation factor 1-alpha

1

0

Small-scale

0.458

High

624672

LRE1
Laminarase-resistance protein LRE1

1

0

Small-scale

0.458

High

624696

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

0

Small-scale

0.458

High

624707

INN1
Ingression protein 1

1

0

Small-scale

0.458

High

624722

CUE5
Ubiquitin-binding protein CUE5

1

0

Small-scale

0.458

High

624724

YL054
Uncharacterized transcriptional regulatory protein YLL054C

1

0

Small-scale

0.458

High

624699

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

4

Small-scale

0.457

High

624708

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

624720

IVY1
Protein IVY1

1

0

High-throughput

0.279

Low

624706

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.265

Low

624689

RPN3
26S proteasome regulatory subunit RPN3

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024