Protein: COX12
Cytochrome c oxidase subunit 12, mitochondrial (Cytochrome c oxidase polypeptide VIb)

Gene: COX12
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: Q01519

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0016491 - oxidoreductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

64273

YP010
UPF0495 protein YPR010C-A

2

0

Small-scale

0.631

High

745246

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

1

High-throughput

0.618

High

781445

MIC60
MICOS complex subunit MIC60

3

0

High-throughput

0.613

High

360345

COX1
Cytochrome c oxidase subunit 1

1

0

High-throughput

0.586

High

360680

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.586

High

399872

COX4
Cytochrome c oxidase subunit 4, mitochondrial

2

1

High-throughput

0.584

High

453194

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

2

2

Small-scale

0.584

High

357779

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

2

0

High-throughput

0.559

High

360903

COX6
Cytochrome c oxidase subunit 6, mitochondrial

2

0

High-throughput

0.559

High

922858

RCF2
Respiratory supercomplex factor 2, mitochondrial

2

0

Small-scale

0.559

High

360753

COX3
Cytochrome c oxidase subunit 3

1

0

Small-scale

0.546

High

613622

ADT2
ADP,ATP carrier protein 2

1

1

Small-scale

0.536

High

357716

CYC1
Cytochrome c isoform 1

1

2

High-throughput

0.479

High

357845

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

1

High-throughput

0.479

High

360806

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

High-throughput

0.479

High

360839

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

1

High-throughput

0.479

High

453306

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

2

High-throughput

0.479

High

465354

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

High-throughput

0.479

High

575991

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

579911

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

622386

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

647273

QCR9
Cytochrome b-c1 complex subunit 9, mitochondrial

1

1

High-throughput

0.479

High

680608

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

1

High-throughput

0.479

High

701559

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

1

High-throughput

0.479

High

752622

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

780509

MCR1
NADH-cytochrome b5 reductase 2

1

1

High-throughput

0.479

High

814951

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

1

High-throughput

0.479

High

823080

YTA12
Mitochondrial inner membrane m-AAA protease component YTA12

1

1

High-throughput

0.479

High

829848

PHB1
Prohibitin-1

1

2

High-throughput

0.479

High

893051

PHB2
Prohibitin-2

1

2

High-throughput

0.479

High

238317

MDM35
Mitochondrial distribution and morphology protein 35

1

0

High-throughput

0.458

High

267949

TIM9
Mitochondrial import inner membrane translocase subunit TIM9

1

0

High-throughput

0.458

High

367262

ATP6
ATP synthase subunit a

1

0

Small-scale

0.458

High

399919

COX8
Cytochrome c oxidase subunit 8, mitochondrial

1

0

High-throughput

0.458

High

417166

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.458

High

432029

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

450462

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

470696

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

0

High-throughput

0.458

High

482212

ATPO
ATP synthase subunit 5, mitochondrial

1

0

High-throughput

0.458

High

519032

COX7
Cytochrome c oxidase subunit 7, mitochondrial

1

0

High-throughput

0.458

High

597695

OM45
Mitochondrial outer membrane protein OM45

1

0

High-throughput

0.458

High

604972

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

732893

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

746591

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

0

High-throughput

0.458

High

746916

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

790398

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

High-throughput

0.458

High

793102

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

803477

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

0

High-throughput

0.458

High

804822

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.458

High

815707

OXA1
Mitochondrial inner membrane protein OXA1

1

0

High-throughput

0.458

High

818634

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

821002

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

0

High-throughput

0.458

High

881418

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

918215

MCY1
Putative mitochondrial cysteine synthase

1

0

High-throughput

0.458

High

925366

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

1030771

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

1030772

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.458

High

357892

CYB
Cytochrome b

1

0

Small-scale

0.426

High

527451

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

742197

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.407

High

515157

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

864806

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

545934

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025