Protein: MKS1
Negative regulator of RAS-cAMP pathway

Gene: MKS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 29
UniProt ID: P34072

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006808 - regulation of nitrogen utilization
GO:0031930 - mitochondria-nucleus signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743617

RTG2
Retrograde regulation protein 2

10

0

Small-scale

0.722

High

709672

BMH1
Protein BMH1

5

1

Small-scale

0.712

High

756611

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

2

0

High-throughput

0.595

High

756604

KOG1
Target of rapamycin complex 1 subunit KOG1

2

0

Small-scale

0.585

High

756600

BMH2
Protein BMH2

2

1

Small-scale

0.584

High

666674

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

Small-scale

0.537

High

756601

TOR1
Serine/threonine-protein kinase TOR1

1

1

High-throughput

0.536

High

756606

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.536

High

756609

SAP4
SIT4-associating protein SAP4

1

1

High-throughput

0.536

High

622913

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

623821

MYO2
Myosin-2

1

0

High-throughput

0.513

High

667128

CG23
G2/mitotic-specific cyclin-3

1

0

High-throughput

0.513

High

721815

XPO1
Exportin-1

1

0

High-throughput

0.513

High

756602

RTG3
Retrograde regulation protein 3

1

0

High-throughput

0.513

High

756612

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

743374

TOR2
Serine/threonine-protein kinase TOR2

1

1

High-throughput

0.479

High

706682

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735476

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.458

High

756613

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

523516

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526316

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

358178

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

544351

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

670545

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

756603

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

756605

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

756607

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

756608

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.426

High

756610

FMP48
Probable serine/threonine-protein kinase FMP48

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025