Protein: RTG2
Retrograde regulation protein 2

Gene: RTG2
Organism: Saccharomyces cerevisiae S288C
Interactions: 81
UniProt ID: P32608

Gene Ontology (top 5):
GO:0000791 - euchromatin
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006606 - protein import into nucleus
GO:0031930 - mitochondria-nucleus signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743617

MKS1
Negative regulator of RAS-cAMP pathway

10

0

Small-scale

0.722

High

743618

BMH2
Protein BMH2

5

1

Small-scale

0.716

High

709646

BMH1
Protein BMH1

4

1

Small-scale

0.686

High

743613

RTG2
Retrograde regulation protein 2

1

1

High-throughput

0.656

High

743619

SPT7
SAGA complex subunit SPT7

2

1

Small-scale

0.635

High

743624

RV167
Reduced viability upon starvation protein 167

2

0

High-throughput

0.595

High

743626

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

743622

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.529

High

743635

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.515

High

743653

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.515

High

721790

XPO1
Exportin-1

1

0

High-throughput

0.513

High

743642

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

574786

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

0

High-throughput

0.493

High

738138

NGG1
SAGA complex subunit NGG1

1

0

Small-scale

0.493

High

743655

ARP6
Actin-like protein ARP6

1

0

High-throughput

0.493

High

743371

TOR2
Serine/threonine-protein kinase TOR2

1

0

High-throughput

0.460

High

743641

STD1
Protein STD1

1

0

Small-scale

0.460

High

475163

CISY2
Citrate synthase, peroxisomal

1

0

Small-scale

0.458

High

514534

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

743614

CHD1
Chromo domain-containing protein 1

1

0

Small-scale

0.458

High

743620

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

743621

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

743627

WRIP1
DNA-dependent ATPase MGS1

1

0

High-throughput

0.458

High

743633

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

Small-scale

0.458

High

743634

SGF73
SAGA complex subunit SGF73

1

0

Small-scale

0.458

High

743639

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.458

High

743640

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

743650

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

481549

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

523406

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

526221

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

544225

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

590582

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

726868

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741220

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

742803

HSP79
Heat shock protein homolog SSE2

1

4

High-throughput

0.445

High

743615

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

743625

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

743647

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

4

High-throughput

0.445

High

743654

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

381026

H2B1
Histone H2B.1

1

1

High-throughput

0.437

High

381457

H2B2
Histone H2B.2

1

1

High-throughput

0.437

High

394379

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

453493

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

569943

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.426

High

592118

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

671603

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

737396

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.426

High

743629

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

743632

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

739571

SPT16
FACT complex subunit SPT16

2

0

High-throughput

0.324

High

743637

NAT10
RNA cytidine acetyltransferase

2

0

High-throughput

0.324

High

738618

EI2BB
Translation initiation factor eIF2B subunit beta

2

0

High-throughput

0.310

High

670495

SIS1
Protein SIS1

2

0

High-throughput

0.298

High

419663

H2A2
Histone H2A.2

1

0

High-throughput

0.269

Low

743628

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.269

Low

743638

H3
Histone H3

1

0

High-throughput

0.269

Low

743643

VPS71
Vacuolar protein sorting-associated protein 71

1

0

High-throughput

0.269

Low

743646

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.269

Low

743648

CORO
Coronin-like protein

1

0

High-throughput

0.269

Low

743652

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.269

Low

381970

H4
Histone H4

1

0

High-throughput

0.249

Low

408564

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

Small-scale

0.249

Low

433530

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

454953

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

504116

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512898

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

679505

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

689346

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

706559

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

743616

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

743630

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

743631

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

743636

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

743644

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

743645

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

743651

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low

531659

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.232

Low

743623

CAJ1
Protein CAJ1

1

0

High-throughput

0.232

Low

743649

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025