Protein: LSM12
Protein LSM12 (Sm-like protein 12)

Gene: LSM12
Organism: Saccharomyces cerevisiae S288C
Interactions: 139
UniProt ID: P38828

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0010494 - cytoplasmic stress granule
GO:0016070 - RNA metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

805616

PBP1
PAB1-binding protein 1

8

5

Small-scale

0.753

High

805642

PBP4
Protein PBP4

4

0

Small-scale

0.653

High

392703

HSP82
ATP-dependent molecular chaperone HSP82

4

0

High-throughput

0.649

High

805626

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

3

0

Small-scale

0.643

High

805595

SSB2
Ribosome-associated molecular chaperone SSB2

3

2

High-throughput

0.634

High

805589

DHH1
ATP-dependent RNA helicase DHH1

2

4

High-throughput

0.614

High

805617

BRE5
UBP3-associated protein BRE5

2

2

High-throughput

0.611

High

805632

POLH
DNA polymerase eta

2

0

Small-scale

0.605

High

805624

MCE1
mRNA-capping enzyme subunit alpha

2

0

High-throughput

0.595

High

805644

PUF3
mRNA-binding protein PUF3

2

1

High-throughput

0.588

High

802161

RS20
Small ribosomal subunit protein uS10

2

1

Small-scale

0.584

High

674613

RS2
Small ribosomal subunit protein uS5

2

0

Small-scale

0.559

High

523884

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.552

High

544806

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

739957

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

2

Small-scale

0.536

High

805654

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

1

High-throughput

0.536

High

805586

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.529

High

805601

SGN1
RNA-binding protein SGN1

1

3

High-throughput

0.515

High

805621

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.515

High

454443

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

744799

ALK2
Serine/threonine-protein kinase Haspin homolog ALK2

1

0

High-throughput

0.513

High

805596

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

805614

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.513

High

805656

HSP42
Heat shock protein 42

1

0

High-throughput

0.513

High

448448

RAD52
DNA repair and recombination protein RAD52

1

0

High-throughput

0.493

High

656961

BUR1
Serine/threonine-protein kinase BUR1

1

0

High-throughput

0.493

High

665179

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.493

High

668487

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.493

High

709743

BMH1
Protein BMH1

1

0

High-throughput

0.493

High

718940

CGS5
S-phase entry cyclin-5

1

0

High-throughput

0.493

High

736484

MDHP
Malate dehydrogenase, peroxisomal

1

0

High-throughput

0.493

High

743203

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.493

High

745428

GYP6
GTPase-activating protein GYP6

1

0

High-throughput

0.493

High

746091

RAD5
DNA repair protein RAD5

1

0

High-throughput

0.493

High

758503

SLD2
DNA replication regulator SLD2

1

0

High-throughput

0.493

High

805506

ORC6
Origin recognition complex subunit 6

1

0

High-throughput

0.493

High

805597

PIG2
GSY2-interacting protein PIG2

1

0

High-throughput

0.493

High

805600

ACA2
ATF/CREB activator 2

1

0

High-throughput

0.493

High

805604

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.493

High

805607

GYP3
GTPase-activating protein GYP3

1

0

High-throughput

0.493

High

805609

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.493

High

805610

ASE1
Anaphase spindle elongation protein

1

0

High-throughput

0.493

High

805612

VPS4
Vacuolar protein sorting-associated protein 4

1

0

High-throughput

0.493

High

805615

NPY1
NAD-capped RNA hydrolase NPY1

1

0

High-throughput

0.493

High

805620

EAF7
Chromatin modification-related protein EAF7

1

0

High-throughput

0.493

High

805629

SGF11
SAGA complex subunit SGF11

1

0

High-throughput

0.493

High

805637

EIS1
Eisosome protein 1

1

0

High-throughput

0.493

High

805640

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.493

High

805645

YL032
KH domain-containing protein YLL032C

1

0

High-throughput

0.493

High

805653

REC8
Meiotic recombination protein REC8

1

0

High-throughput

0.493

High

805628

DIG1
Down-regulator of invasive growth 1

1

0

High-throughput

0.486

High

805631

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.486

High

403504

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

3

Small-scale

0.479

High

721609

RENT1
ATP-dependent helicase NAM7

1

2

Small-scale

0.479

High

747351

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

805591

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

2

High-throughput

0.479

High

805613

VID30
GID complex subunit 1

1

1

High-throughput

0.479

High

805623

NAM8
Protein NAM8

1

3

High-throughput

0.479

High

805648

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.479

High

805651

YRA1
RNA annealing protein YRA1

1

3

Small-scale

0.479

High

149753

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

382091

H4
Histone H4

1

0

Small-scale

0.458

High

410121

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

432573

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

433631

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

434563

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.458

High

435078

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

435954

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

455053

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

514630

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

561474

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

570009

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

666451

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

684718

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

707044

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734969

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

743522

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.458

High

751395

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

778321

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

780825

MUD2
Splicing factor MUD2

1

0

Small-scale

0.458

High

792035

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

797737

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

805588

STM1
Suppressor protein STM1

1

0

Small-scale

0.458

High

805592

ARB1
ABC transporter ATP-binding protein ARB1

1

0

Small-scale

0.458

High

805598

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.458

High

805599

TM108
Protein TMA108

1

0

High-throughput

0.458

High

805606

JHD2
Histone demethylase JHD2

1

0

Small-scale

0.458

High

805608

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

805611

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

805618

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.458

High

805619

IGO1
mRNA stability protein IGO1

1

0

Small-scale

0.458

High

805622

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

805627

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

805633

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.458

High

805634

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

805635

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

805639

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

805641

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

805643

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

805646

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.458

High

805647

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

805649

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.458

High

805650

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

805652

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

805657

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.458

High

805660

SUS1
SAGA complex subunit SUS1

1

0

Small-scale

0.458

High

526646

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

780598

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.438

High

805603

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.437

High

394539

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

592235

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

805602

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

753359

RS3A1
Small ribosomal subunit protein eS1A

2

0

High-throughput

0.305

High

367962

ENO2
Enolase 2

1

0

High-throughput

0.279

Low

797290

YSW1
Spore-specific protein YSW1

1

0

High-throughput

0.269

Low

801995

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

0

High-throughput

0.269

Low

803336

YHA8
Uncharacterized transporter YHL008C

1

0

High-throughput

0.269

Low

805593

RSM18
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.269

Low

805594

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.269

Low

805605

IRC8
Uncharacterized protein IRC8

1

0

High-throughput

0.269

Low

805625

ARG56
Protein ARG5,6, mitochondrial [Cleaved into: N-acetyl-gamma-glutamyl-phosphate reductase

1

0

High-throughput

0.269

Low

805636

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.269

Low

805638

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit BLS1

1

0

High-throughput

0.269

Low

805655

PRR2
Serine/threonine-protein kinase PRR2

1

0

High-throughput

0.261

Low

383692

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

441897

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

482012

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.249

Low

503034

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504202

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512430

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

513000

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

689444

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

794976

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

796859

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.249

Low

805587

TEM1
Protein TEM1

1

0

High-throughput

0.249

Low

805590

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

805630

PEX29
Peroxisomal membrane protein PEX29

1

0

Small-scale

0.249

Low

805658

NOP58
Nucleolar protein 58

1

0

High-throughput

0.249

Low

805659

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025