Protein: SLK19
Kinetochore protein SLK19 (Synthetic lethal KAR3 protein 19)

Gene: SLK19
Organism: Saccharomyces cerevisiae S288C
Interactions: 49
UniProt ID: Q08581

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005737 - cytoplasm
GO:0005816 - spindle pole body
GO:0005819 - spindle
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1064508

SLK19
Kinetochore protein SLK19

5

19

Small-scale

0.712

High

826901

DSN1
Kinetochore-associated protein DSN1

4

0

Small-scale

0.643

High

795758

STU1
Protein STU1

2

2

Small-scale

0.624

High

740022

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

2

9

Small-scale

0.611

High

1040555

ESP1
Separin

2

1

Small-scale

0.601

High

364781

CDK1
Cyclin-dependent kinase 1

1

13

High-throughput

0.578

High

917742

KNL1
Outer kinetochore KNL1 complex subunit SPC105

2

0

High-throughput

0.576

High

672125

PUF4
Pumilio homology domain family member 4

1

1

High-throughput

0.515

High

814294

RV167
Reduced viability upon starvation protein 167

1

8

High-throughput

0.515

High

808611

SMC2
Structural maintenance of chromosomes protein 2

1

14

High-throughput

0.508

High

818065

LSM4
LSM complex subunit LSM4

1

3

High-throughput

0.508

High

894350

ASE1
Anaphase spindle elongation protein

1

20

Small-scale

0.501

High

750792

PRS6A
26S proteasome regulatory subunit 6A

1

5

High-throughput

0.481

High

897518

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

924112

CNM67
Chaotic nuclear migration protein 67

1

18

High-throughput

0.481

High

999501

DID2
Vacuolar protein-sorting-associated protein 46

1

1

High-throughput

0.481

High

1046230

VPS20
Vacuolar protein sorting-associated protein 20

1

8

High-throughput

0.481

High

755312

NUF2
Kinetochore protein NUF2

1

10

High-throughput

0.479

High

1042256

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

1064509

SCC1
Sister chromatid cohesion protein 1

1

2

Small-scale

0.479

High

1064510

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.470

High

1059346

BRE1
E3 ubiquitin-protein ligase BRE1

1

20

High-throughput

0.464

High

438340

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.460

High

790462

PAM1
Protein PAM1

1

0

High-throughput

0.460

High

802536

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.460

High

813866

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.460

High

864886

MAD3
Spindle assembly checkpoint component MAD3

1

0

Small-scale

0.458

High

866075

NNF1
Kinetochore-associated protein NNF1

1

0

Small-scale

0.458

High

527885

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

548732

RNA1
Ran GTPase-activating protein 1

1

10

High-throughput

0.439

High

756667

NIC96
Nucleoporin NIC96

1

1

High-throughput

0.439

High

776395

YET1
Endoplasmic reticulum transmembrane protein 1

1

13

High-throughput

0.439

High

779589

LHS1
Heat shock protein 70 homolog LHS1

1

11

High-throughput

0.439

High

836598

SPR3
Sporulation-regulated protein 3

1

3

High-throughput

0.439

High

866200

SGM1
Protein SGM1

1

17

High-throughput

0.439

High

1040467

SPP1
COMPASS component SPP1

1

5

High-throughput

0.439

High

594609

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

708401

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

1038505

PT191
Mitochondrial protein PET191

1

0

High-throughput

0.282

High

725986

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.251

Low

780889

STB6
Protein STB6

1

0

High-throughput

0.251

Low

849710

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

869277

TEA1
TY1 enhancer activator

1

0

High-throughput

0.251

Low

918777

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

1044405

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.251

Low

1045083

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

661569

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

745549

TIM12
Mitochondrial import inner membrane translocase subunit TIM12

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025