Protein: UPF3
Nonsense-mediated mRNA decay protein 3 (Up-frameshift suppressor 3)

Gene: UPF3
Organism: Saccharomyces cerevisiae S288C
Interactions: 37
UniProt ID: P48412

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

804856

NMD2
Nonsense-mediated mRNA decay protein 2

7

0

Small-scale

0.910

High

721637

RENT1
ATP-dependent helicase NAM7

6

0

Small-scale

0.692

High

815171

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.586

High

430881

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

Small-scale

0.537

High

722077

XPO1
Exportin-1

1

0

High-throughput

0.513

High

836548

T2FB
Transcription initiation factor IIF subunit beta

1

0

High-throughput

0.493

High

676745

GBP2
Serine/arginine

1

1

Small-scale

0.479

High

743403

TOR2
Serine/threonine-protein kinase TOR2

1

0

High-throughput

0.460

High

365654

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.458

High

381563

H2B2
Histone H2B.2

1

0

High-throughput

0.458

High

432627

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

435211

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

442002

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

672914

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

707572

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

740989

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

764113

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

792134

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

807677

HRB1
Serine/arginine

1

0

Small-scale

0.458

High

871840

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

871841

H3
Histone H3

1

0

High-throughput

0.458

High

871842

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

1

0

High-throughput

0.458

High

871843

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

871845

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.458

High

871846

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

871847

SGO1
Shugoshin

1

0

High-throughput

0.458

High

524475

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527104

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

811471

XDJ1
DnaJ protein homolog XDJ1

1

0

High-throughput

0.426

High

816293

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

383786

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

455151

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503133

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504303

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513103

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

747463

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

871844

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025