Protein: NMD2
Nonsense-mediated mRNA decay protein 2 (Up-frameshift suppressor 2)

Gene: NMD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 90
UniProt ID: P38798

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0006310 - DNA recombination
GO:0035145 - exon-exon junction complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

721608

RENT1
ATP-dependent helicase NAM7

16

2

Small-scale

0.981

High

804856

UPF3
Nonsense-mediated mRNA decay protein 3

7

0

Small-scale

0.910

High

804860

DBP6
ATP-dependent RNA helicase DBP6

1

0

Small-scale

0.687

High

523865

HSP71
Heat shock protein SSA1

2

0

High-throughput

0.576

High

430844

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

Small-scale

0.561

High

721919

XPO1
Exportin-1

1

2

High-throughput

0.536

High

794174

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.517

High

804875

SKI7
Superkiller protein 7

1

1

Small-scale

0.515

High

504677

YH41B
Transposon Ty4-H Gag-Pol polyprotein

1

0

High-throughput

0.493

High

712786

CHS3
Chitin synthase 3

1

0

High-throughput

0.493

High

803195

RIM4
Meiotic activator RIM4

1

0

High-throughput

0.493

High

676724

GBP2
Serine/arginine

1

1

Small-scale

0.479

High

802784

OSH3
Oxysterol-binding protein homolog 3

1

1

Small-scale

0.479

High

804839

CSK2C
Casein kinase II subunit beta'

1

1

Small-scale

0.479

High

804851

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.479

High

804865

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.460

High

365617

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.458

High

550760

INO1
Inositol-3-phosphate synthase

1

0

Small-scale

0.458

High

570005

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

625959

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

Small-scale

0.458

High

677386

KRR1
KRR1 small subunit processome component

1

0

Small-scale

0.458

High

740911

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

804837

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

High-throughput

0.458

High

804838

HRB1
Serine/arginine

1

0

Small-scale

0.458

High

804855

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

Small-scale

0.458

High

804857

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.458

High

804868

PNG1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

0

High-throughput

0.458

High

804870

SCW10
Probable family 17 glucosidase SCW10

1

0

Small-scale

0.458

High

804874

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

804879

HUA2
Protein HUA2

1

0

Small-scale

0.458

High

804881

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.458

High

804885

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

0

Small-scale

0.458

High

392695

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

544788

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

675982

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

741529

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

804844

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

804862

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

473520

LEUR
Regulatory protein LEU3

1

1

Small-scale

0.437

High

585929

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.437

High

622946

CSK22
Casein kinase II subunit alpha'

1

1

Small-scale

0.437

High

804845

RFC2
Replication factor C subunit 2

1

1

Small-scale

0.437

High

804852

BBC1
Myosin tail region-interacting protein MTI1

1

2

Small-scale

0.437

High

804878

NOP53
Ribosome biogenesis protein NOP53

1

1

Small-scale

0.437

High

727005

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

804147

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

804842

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

804849

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

804853

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

804861

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

804882

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

670681

SIS1
Protein SIS1

1

1

High-throughput

0.407

High

804859

YG5L
Uncharacterized protein YGR266W

2

0

Small-scale

0.305

High

804884

SUS1
SAGA complex subunit SUS1

2

0

Small-scale

0.305

High

804846

MSL1
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.269

Low

804848

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.269

Low

804863

SUR7
Protein SUR7

1

0

High-throughput

0.269

Low

454299

CARP
Saccharopepsin

1

0

High-throughput

0.249

Low

534261

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

Small-scale

0.249

Low

618868

GAP1
General amino-acid permease GAP1

1

0

Small-scale

0.249

Low

633158

MAK11
Protein MAK11

1

0

Small-scale

0.249

Low

645248

GAS1
1,3-beta-glucanosyltransferase GAS1

1

0

Small-scale

0.249

Low

662698

EXG1
Glucan 1,3-beta-glucosidase I/II

1

0

Small-scale

0.249

Low

697765

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

0

High-throughput

0.249

Low

698177

KTR1
Alpha-1,2 mannosyltransferase KTR1

1

0

Small-scale

0.249

Low

700003

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

Small-scale

0.249

Low

707027

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

720835

ITR1
Myo-inositol transporter 1

1

0

Small-scale

0.249

Low

758062

ASH1
Transcriptional regulatory protein ASH1

1

0

High-throughput

0.249

Low

791054

NOP4
Nucleolar protein 4

1

0

Small-scale

0.249

Low

793840

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

Small-scale

0.249

Low

797476

TOS1
Probable circularly permuted 1,3-beta-glucanase TOS1

1

0

Small-scale

0.249

Low

804840

PSD1
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial

1

0

Small-scale

0.249

Low

804841

MNN9
Mannan polymerase complexes subunit MNN9

1

0

Small-scale

0.249

Low

804843

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

Small-scale

0.249

Low

804847

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

804850

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

Small-scale

0.249

Low

804854

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

Small-scale

0.249

Low

804858

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.249

Low

804864

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

1

0

High-throughput

0.249

Low

804867

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

Small-scale

0.249

Low

804869

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

804871

OMS1
Methyltransferase OMS1, mitochondrial

1

0

Small-scale

0.249

Low

804873

UTP4
U3 small nucleolar RNA-associated protein 4

1

0

Small-scale

0.249

Low

804876

ETFD
Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.249

Low

804877

AP1G1
AP-1 complex subunit gamma-1

1

0

Small-scale

0.249

Low

804880

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

804883

MPD1
Protein disulfide-isomerase MPD1

1

0

Small-scale

0.249

Low

804866

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

804872

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025