Protein: SORC2
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

Gene: SORC2, SORCS2
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q96PQ0

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0007218 - neuropeptide signaling pathway
GO:0008188 - neuropeptide receptor activity
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376948

NGF
Beta-nerve growth factor

1

7

Small-scale

0.647

High

634973

NTF3
Neurotrophin-3

1

7

Small-scale

0.579

High

660292

BDNF
Neurotrophic factor BDNF precursor form

1

7

Small-scale

0.579

High

1399915

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.536

High

1399911

TTC1
Tetratricopeptide repeat protein 1

1

0

High-throughput

0.513

High

1399912

CSTFT
Cleavage stimulation factor subunit 2 tau variant

1

0

High-throughput

0.513

High

1399913

NXT2
NTF2-related export protein 2

1

0

High-throughput

0.513

High

466589

TNR16
Tumor necrosis factor receptor superfamily member 16

1

8

Small-scale

0.501

High

1027677

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.493

High

1399916

MYH4
Myosin-4

1

2

High-throughput

0.489

High

1140717

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1393192

TM169
Transmembrane protein 169

1

0

High-throughput

0.426

High

1399914

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

399728

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

0

High-throughput

0.279

Low

1208949

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.279

Low

1041688

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

Small-scale

0.249

Low

1331841

SYT2
Synaptotagmin-2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025