Protein: IKS1
Probable serine/threonine-protein kinase IKS1 (EC 2.7.11.1) (IRA1 kinase suppressor 1)

Gene: IKS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: P47042

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

670877

SIS1
Protein SIS1

1

9

High-throughput

0.691

High

864414

DSK2
Ubiquitin domain-containing protein DSK2

1

6

High-throughput

0.691

High

864417

YG5B
Uncharacterized RNA-binding protein YGR250C

1

7

High-throughput

0.691

High

864447

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

11

High-throughput

0.691

High

694149

CDC15
Cell division control protein 15

1

17

High-throughput

0.647

High

740185

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.647

High

864442

CMR3
Zinc finger protein CRM3

1

2

High-throughput

0.647

High

739983

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

18

High-throughput

0.621

High

740974

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

12

High-throughput

0.618

High

864412

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.614

High

864410

MPS3
Spindle pole body assembly component MPS3

2

0

High-throughput

0.569

High

550592

SST2
Protein SST2

1

0

Small-scale

0.549

High

666493

DBP2
ATP-dependent RNA helicase DBP2

1

5

High-throughput

0.536

High

864422

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

1

High-throughput

0.536

High

864423

NAB6
RNA-binding protein NAB6

1

0

High-throughput

0.513

High

864437

PBP4
Protein PBP4

1

0

High-throughput

0.513

High

455580

SYSC
Serine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.501

High

504593

YH11A
Transposon Ty1-H Gag polyprotein

1

4

High-throughput

0.501

High

585639

STI1
Heat shock protein STI1

1

7

High-throughput

0.501

High

726162

2AAA
Protein phosphatase PP2A regulatory subunit A

1

6

High-throughput

0.501

High

806267

ADY1
Prospore formation at selected spindle poles protein 1

1

1

High-throughput

0.501

High

813292

FHP
Flavohemoprotein

1

3

High-throughput

0.501

High

828272

SYA
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.501

High

845896

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

1

High-throughput

0.501

High

858103

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.501

High

864411

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

3

High-throughput

0.501

High

864429

GYL1
Probable GTPase-activating protein GYL1

1

3

High-throughput

0.501

High

864430

YM11A
Transposon Ty1-ML1 Gag polyprotein

1

5

High-throughput

0.501

High

864443

YRR1
Zinc finger transcription factor YRR1

1

1

High-throughput

0.501

High

864446

NCB2
Negative cofactor 2 complex subunit beta

1

1

High-throughput

0.501

High

557742

SRS2
ATP-dependent DNA helicase SRS2

1

2

Small-scale

0.481

High

864421

CENPP
Inner kinetochore subunit CTF19

1

1

High-throughput

0.481

High

700020

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.480

High

723617

MLS1
Malate synthase 1

1

0

High-throughput

0.480

High

780553

SHE2
SWI5-dependent HO expression protein 2

1

0

High-throughput

0.480

High

814078

MTW1
Kinetochore-associated protein MTW1

1

0

High-throughput

0.480

High

818386

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

0

High-throughput

0.480

High

864413

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.480

High

864415

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.480

High

864416

TAL2
Transaldolase NQM1

1

0

High-throughput

0.480

High

864418

RAGAB
GTP-binding protein GTR1

1

0

High-throughput

0.480

High

864425

EKI1
Ethanolamine kinase

1

0

High-throughput

0.480

High

864426

ACL4
Assembly chaperone of RPL4

1

0

High-throughput

0.480

High

864428

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.480

High

864431

DON1
Donuts protein 1

1

0

High-throughput

0.480

High

864432

YL287
Uncharacterized protein YLR287C

1

0

High-throughput

0.480

High

864433

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.480

High

864434

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.480

High

864440

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.480

High

864441

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.480

High

864444

TRM13
tRNA:m(4)X modification enzyme TRM13

1

0

High-throughput

0.480

High

864445

NKP1
Inner kinetochore subunit NKP1

1

0

High-throughput

0.480

High

864439

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

383149

RLA4
Large ribosomal subunit protein P2B

1

4

High-throughput

0.457

High

452034

TOM70
Mitochondrial import receptor subunit TOM70

1

8

High-throughput

0.457

High

609229

CLC1
Clathrin light chain

1

2

High-throughput

0.457

High

737098

CDC11
Cell division control protein 11

1

5

High-throughput

0.457

High

744712

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

1

High-throughput

0.457

High

864419

NUP49
Nucleoporin NUP49/NSP49

1

2

High-throughput

0.457

High

864420

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.457

High

864436

IMH1
Golgin IMH1

1

9

High-throughput

0.457

High

864427

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.282

High

813412

PO152
Nucleoporin POM152

1

0

High-throughput

0.265

Low

515022

MTCU2
Copper metallothionein 1-2

1

0

High-throughput

0.261

Low

849503

CWP2
Cell wall protein CWP2

1

0

High-throughput

0.261

Low

864435

VTA1
Vacuolar protein sorting-associated protein VTA1

1

0

High-throughput

0.261

Low

864438

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.261

Low

795074

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

864424

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low

828527

HACD
Very-long-chain

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025