Protein: CO8A
Complement component C8 alpha chain (Complement component 8 subunit alpha)

Gene: CO8A, C8A
Organism: Homo sapiens
Interactions: 22
UniProt ID: P07357

Gene Ontology (top 5):
GO:0001848 - complement binding
GO:0005576 - extracellular region
GO:0005579 - membrane attack complex
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

456933

CO8G
Complement component C8 gamma chain

1

2

Small-scale

0.647

High

388813

CO9
Complement component C9 [Cleaved into: Complement component C9a; Complement component C9b]

1

15

Small-scale

0.618

High

456932

CO8B
Complement component C8 beta chain

1

16

High-throughput

0.618

High

456943

NTCP
Hepatic sodium/bile acid cotransporter

2

1

High-throughput

0.606

High

456950

GP152
Probable G-protein coupled receptor 152

2

1

High-throughput

0.606

High

456938

CTR1
High affinity cationic amino acid transporter 1

2

0

High-throughput

0.580

High

456947

GOT1A
Vesicle transport protein GOT1A

2

0

High-throughput

0.580

High

456949

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.580

High

456936

IDE
Insulin-degrading enzyme

2

0

High-throughput

0.576

High

456937

FBLN1
Fibulin-1

1

14

High-throughput

0.575

High

456934

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.536

High

456940

MMP14
Matrix metalloproteinase-14

1

5

High-throughput

0.536

High

456942

MESD
LRP chaperone MESD

1

1

High-throughput

0.536

High

456939

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

456941

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.513

High

456935

CD59
CD59 glycoprotein

1

1

Small-scale

0.501

High

456945

RSH4A
Radial spoke head protein 4 homolog A

1

0

High-throughput

0.493

High

456952

FBX2
F-box only protein 2

1

12

High-throughput

0.489

High

456944

TAF7
Transcription initiation factor TFIID subunit 7

2

0

High-throughput

0.313

High

456948

CMIP
C-Maf-inducing protein

1

0

High-throughput

0.279

Low

456951

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.279

Low

456946

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025